Anti-MCM5 抗体 [CRCT5.1 (A2.7A3)] (ab6154)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCM5 antibody [CRCT5.1 (A2.7A3)] (ab6154)](https://www.abcam.co.jp/ps/products/6/ab6154/Images/ab6154_1.jpg "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCM5 antibody [CRCT5.1 (A2.7A3)] (ab6154)")
Key features and details
- Mouse monoclonal [CRCT5.1 (A2.7A3)] to MCM5
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
製品の概要
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製品名
Anti-MCM5 antibody [CRCT5.1 (A2.7A3)]
MCM5 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [CRCT5.1 (A2.7A3)] to MCM5 -
由来種
Mouse -
特異性
Recognises human Mcm-5 -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human -
免疫原
Bacterially expressed human Mcm5
-
ポジティブ･コントロール
- Cervical Carcinoma Tissue
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特記事項
Clone Number: CRCT5.1 (A2.7A3)Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Preservative: 0.1% Sodium azide -
Concentration information loading... -
精製度
Protein G purified -
特記事項（精製）
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant -
ポリ/モノ
モノクローナル -
クローン名
CRCT5.1 (A2.7A3) -
ミエローマ
Sp2 -
アイソタイプ
IgG2b -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
Our Abpromise guarantee covers the use of ab6154 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | 1/25 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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配列類似性
Belongs to the MCM family.
Contains 1 MCM domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 4174 Human
- Omim: 602696 Human
- SwissProt: P33992 Human
- Unigene: 517582 Human
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別名
- CDC 46 antibody
- CDC46 antibody
- CDC46 homolog antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MCM5 antibody [CRCT5.1 (A2.7A3)] (ab6154)ab6154 staining MCM5 in human tonsil by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
プロトコール
参考文献 (6)
ab6154 は 6 報の論文で使用されています。
- Lin JX et al. CDK5RAP3 inhibits angiogenesis in gastric neuroendocrine carcinoma by modulating AKT/HIF-1a/VEGFA signaling. Cancer Cell Int 19:282 (2019). PubMed: 31728130
- Mishra S et al. Cross-talk between Lysine-Modifying Enzymes Controls Site-Specific DNA Amplifications. Cell 174:803-817.e16 (2018). PubMed: 30057114
- Yin Y & Rothenberg E Probing the Spatial Organization of Molecular Complexes Using Triple-Pair-Correlation. Sci Rep 6:30819 (2016). PubMed: 27545293
- Munday DC et al. Interactome analysis of the human respiratory syncytial virus RNA polymerase complex identifies protein chaperones as important cofactors that promote L-protein stability and RNA synthesis. J Virol 89:917-30 (2015). PubMed: 25355874
- Rakotomalala L et al. Hepatitis B virus X protein increases the Cdt1-to-geminin ratio inducing DNA re-replication and polyploidy. J Biol Chem 283:28729-40 (2008). ICC/IF ; Mouse . PubMed: 18693245
- Williams GH et al. Improved cervical smear assessment using antibodies against proteins that regulate DNA replication. Proc Natl Acad Sci U S A 95:14932-7 (1998). PubMed: 9843993
