Anti-MAGEA1 抗体 [SPM282] - BSA and Azide free (ab269794)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody (ab269794)

    Key features and details

    • Mouse monoclonal [SPM282] to MAGEA1 - BSA and Azide free
    • Suitable for: IHC-P
    • Reacts with: Human
    • Isotype: IgG1

    製品の概要

    • 製品名

      Anti-MAGEA1 antibody [SPM282] - BSA and Azide free
      MAGEA1 一次抗体 製品一覧

    • 製品の詳細

      Mouse monoclonal [SPM282] to MAGEA1 - BSA and Azide free

    • 由来種

      Mouse

    • 特異性

      ab25834 recognises MAGE-1.

    • Tested Applications & Species

      Application Species
      IHC-P
      Human
      See all applications and species data

    • 免疫原

      Recombinant full length protein corresponding to Human MAGEA1.

    • ポジティブ･コントロール

      • Colo32 cells Germ cells in testis.

    • 特記事項

      ab269794 is a carrier free version of ab25834. This format is designed for use in antibody labeling, including fluorochromes, metal isotypes, oligonucleotides, enzymes.  This product was previously labelled as MAGE 1

       

    製品の特性

    アプリケーション

    The Abpromise guarantee

    Our Abpromise guarantee covers the use of ab269794 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Guaranteed

    Tested applications are guaranteed to work and covered by our Abpromise guarantee.

    Predicted

    Predicted to work for this combination of applications and species but not guaranteed.

    Incompatible

    Does not work for this combination of applications and species.

    アプリケーション Species
    IHC-P
    Human
    All applications
    Rat
    Dog
    アプリケーション Abreviews 特記事項
    IHC-P
    1/25. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
    特記事項
    IHC-P
    1/25. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    ターゲット情報

    • 機能

      May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

    • 組織特異性

      Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors, leukemias and lymphomas.

    • 配列類似性

      Contains 1 MAGE domain.

    • 細胞内局在

      Cytoplasm. Nucleus.
    • Information by UniProt

    • 参照データベース

      • 別名

        • Antigen MZ2 E antibody
        • Antigen MZ2-E antibody
        • Cancer/testis antigen 1.1 antibody
        • cancer/testis antigen family 1, member 1 antibody
        • CT1.1 antibody
        • MAGA1_HUMAN antibody
        • MAGE 1 antigen antibody
        • MAGE-1 antigen antibody
        • MAGE1 antibody
        • MAGE1A antibody
        • MAGEA1 antibody
        • Melanoma antigen 1 antibody
        • Melanoma antigen family A 1 (directs expression of antigen MZ2 E) antibody
        • Melanoma antigen family A 1 antibody
        • Melanoma antigen MAGE 1 antibody
        • Melanoma associated antigen 1 antibody
        • Melanoma associated antigen MZ2 E antibody
        • Melanoma-associated antigen 1 antibody
        • MGC9326 antibody
        see all

      画像

      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody (ab269794)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGEA1 antibody (ab269794)

        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human testis tissue labelling MAGEA1 with ab25834.

        This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab25834).

      プロトコール

      To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

      Click here to view the general protocols

      参考文献 (0)

      ab269794 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

      ab269794 は論文での使用が確認できていません。

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