LY 303511 dihydrochloride, Negative control for LY 294002 (ab120956)
Key features and details
- Negative control for LY 294002 (ab120243)
- CAS Number: 154447-38-8
- Purity: > 98%
- Soluble in DMSO to 100 mM, in ethanol to 100 mM and in 1 eq. HCl to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
LY 303511 dihydrochloride, Negative control for LY 294002 -
製品の詳細
Negative control for LY 294002 (ab120243) -
生理活性の詳細
Negative control for LY 294002 (ab120243). PI3K inhibitory activity. Inhibits voltage-gated Kv channel activity (IC50 = 64.6 μM). Various pharmacological effects including inhibition of LPS-stimulated FPR1 expression and induction of H2O2 production.
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精製度
> 98% -
CAS 番号
154447-38-8 -
構造式
製品の特性
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体系名
8-Phenyl-2-(1-piperazinyl)-4H-1-benzopyran-4-one dihydrochloride -
分子量
379.29 -
分子式
C19H18N2O2.2HCl -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM, in ethanol to 100 mM and in 1 eq. HCl to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
Cl.Cl.O=C2C=C(Oc1c(cccc12)c3ccccc3)N4CCNCC4 -
由来
Synthetic
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研究分野
画像
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (1)
ab120956 は 1 報の論文で使用されています。
- Li H et al. Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-238 (2018). PubMed: 29559323