LX-1031, TPH1 inhibitor (ab269814)
Key features and details
- TPH1 inhibitor
- CAS Number: 945976-76-1
Soluble in water to 5 mM and in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
-
製品名
LX-1031, TPH1 inhibitor -
製品の詳細
TPH1 inhibitor -
生理活性の詳細
Small molecule inhibitor of tryptophan 5-hydroxylase (TPH). A heterocyclic substituted phenylalanine analog. Inhibits TPH1 in vitro in the concentration range 10-7 - 10-8 M. Reduces synthesis of serotonin (5-HT) peripherally and is being developed for conditions characterized by excess 5-HT expression such as diarrhea-predominant irritable bowel syndrome (IBS-D) and possibly carcinoid diarrhea.
-
CAS 番号
945976-76-1 -
構造式
製品の特性
-
体系名
4-[2-Amino-6-[(1R)-2,2,2-trifluoro-1-(3'-methoxy[1,1'-biphenyl]-4- yl)ethoxy]-4-pyrimidinyl]-L-phenylalanine
-
分子量
538.52 -
分子式
C28H25F3N4O4 -
PubChem 登録番号
23633604 -
保存方法
Shipped at room temperature. Store at -20°C. -
溶解性
Soluble in water to 5 mM and in DMSO to 50 mM
-
使用に関する注意
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
SMILES 線形表記
COC1=CC=CC(=C1)C2=CC=C(C=C2)[C@H](C(F)(F)F)OC3=NC(=NC(=C3)C4=CC=C(C=C4)C[C@@H](C(=O)O)N)N -
由来
Synthetic
画像
-
Chemical Structure - LX-1031, TPH1 inhibitor (ab269814)
Chemical structure of LX-1031, TPH1 inhibitor, 945976-76-1
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (0)
ab269814 は論文での使用が確認できていません。