Anti-Liver Arginase 抗体 (ab92274)
Key features and details
- Goat polyclonal to Liver Arginase
- Suitable for: WB
- Reacts with: Mouse, Rat, Human, Pig
- Isotype: IgG
製品の概要
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製品名
Anti-Liver Arginase antibody
Liver Arginase 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Liver Arginase -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse, Rat, Human, Pig
交差が予測される動物種: Rabbit, Cow, Dog -
免疫原
Synthetic peptide:
CFGLAREGNHKPID
, corresponding to C terminal amino acids 303-316 of Human liver Arginase (NP_000036.2). -
ポジティブ・コントロール
- WB: Pig, mouse, human and rat liver lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Assay kits
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92274の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 35 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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パスウェイ
Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1. -
関連疾患
Defects in ARG1 are the cause of argininemia (ARGIN) [MIM:207800]; also known as hyperargininemia. Argininemia is a rare autosomal recessive disorder of the urea cycle. Arginine is elevated in the blood and cerebrospinal fluid, and periodic hyperammonemia occurs. Clinical manifestations include developmental delay, seizures, mental retardation, hypotonia, ataxia, progressive spastic quadriplegia. -
配列類似性
Belongs to the arginase family. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 383 Human
- Entrez Gene: 11846 Mouse
- Entrez Gene: 29221 Rat
- Omim: 608313 Human
- SwissProt: P05089 Human
- SwissProt: Q61176 Mouse
- SwissProt: P07824 Rat
- Unigene: 440934 Human
see all -
別名
- A I antibody
- Al antibody
- ARG 1 antibody
see all
画像
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All lanes : Anti-Liver Arginase antibody (ab92274) at 0.03 µg/ml
Lane 1 : pig liver tissue lysate
Lane 2 : mouse liver tissue lysate
Lane 3 : rat liver tissue lysate
Lysates/proteins at 35 µg per lane.
Predicted band size: 35 kDa
Observed band size: 35 kDa -
Anti-Liver Arginase antibody (ab92274) at 0.01 µg/ml + human liver lysate in RIPA buffer at 35 µg
Predicted band size: 35 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab92274 は 3 報の論文で使用されています。
- Han GH et al. Transplantation of tauroursodeoxycholic acid-inducing M2-phenotype macrophages promotes an anti-neuroinflammatory effect and functional recovery after spinal cord injury in rats. Cell Prolif 54:e13050 (2021). PubMed: 33960559
- Hashimoto T et al. Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. J Invest Dermatol 140:850-859.e3 (2020). PubMed: 31626785
- Kim SJ et al. Anti-inflammatory effect of Tauroursodeoxycholic acid in RAW 264.7 macrophages, Bone marrow-derived macrophages, BV2 microglial cells, and spinal cord injury. Sci Rep 8:3176 (2018). PubMed: 29453346