Anti-Listeriolysin (LLO) 抗体 (ab200538)
Key features and details
- Rabbit polyclonal to Listeriolysin (LLO)
- Suitable for: ELISA, WB
- Reacts with: Listeria monocytogenes
- Isotype: IgG
製品の概要
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製品名
Anti-Listeriolysin (LLO) antibody -
製品の詳細
Rabbit polyclonal to Listeriolysin (LLO) -
由来種
Rabbit -
アプリケーション
適用あり: ELISA, WBmore details -
種交差性
交差種: Listeria monocytogenes -
免疫原
Recombinant full length protein corresponding to Listeriolysin (LLO). (Expressed in E.coli).
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特記事項
Listeriolysin O (LLO), a major virulence factor produced by all pathogenic strains of
L. monocytogenes, has been identified as a candidate antigen for a serological assay.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
Constituents: 2.94% Sodium citrate, 0.61% Tris, 0.05% Glycerol -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab200538の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
1/1500 - 1/3000.
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WB |
1/1000 - 1/1500. Detects a band of approximately 56 kDa (predicted molecular weight: 59 kDa).
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特記事項 |
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ELISA
1/1500 - 1/3000. |
WB
1/1000 - 1/1500. Detects a band of approximately 56 kDa (predicted molecular weight: 59 kDa). |
ターゲット情報
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関連性
Listeria monocyogenes is a faculative intracellular Gram-positive food borne bacterium, increasingly recognized as being responsible for severe infections in both humans and animals. Ingestion of contaminated food causes an infection called Listeriosis, which affects especially immunocomprimised patients, new borns and pregnant women. It is characterized by severe syndromes such as encephalitis, meningoencephalitis, septicemia and abortion. Listeriolysin O (LLO) is a single polypeptide protein secreted by the Gram-positive bacterium Listeria monocytogenes. LLO belongs to the group of cholesterol-binding sulfhydrylactivated toxins, the lytic activity of which is enhanced by reducing agents and is suppressed by exposure to oxygen or cholesterol. LLO hemolytic activity is maximum at pH 5.5 and rapidly decreases with the increase of the pH. -
参照データベース
- Entrez Gene: 2797098 Listeria monocytogenes
- Entrez Gene: 987033 Listeria monocytogenes
- SwissProt: P13128 Listeria monocytogenes
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別名
- hly antibody
- hlyA antibody
- lisA antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (15)
ab200538 は 15 報の論文で使用されています。
- Tingting W et al. Amentoflavone attenuates Listeria monocytogenes pathogenicity through an LLO-dependent mechanism. Br J Pharmacol 179:3839-3858 (2022). PubMed: 35229287
- Mayer RL et al. Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes. Nat Commun 13:6075 (2022). PubMed: 36241641
- Tan JMJ et al. Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes. Nat Commun 12:4999 (2021). PubMed: 34404769
- Bai X et al. Biofilm-isolated Listeria monocytogenes exhibits reduced systemic dissemination at the early (12-24?h) stage of infection in a mouse model. NPJ Biofilms Microbiomes 7:18 (2021). PubMed: 33558519
- Ignatov D et al. An mRNA-mRNA Interaction Couples Expression of a Virulence Factor and Its Chaperone in Listeria monocytogenes. Cell Rep 30:4027-4040.e7 (2020). PubMed: 32209466