Anti-LIPG 抗体 (ab24447)
Key features and details
- Rabbit polyclonal to LIPG
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Mouse, Rat, Sheep, Human, Pig
- Isotype: IgG
製品の概要
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製品名
Anti-LIPG antibody -
製品の詳細
Rabbit polyclonal to LIPG -
由来種
Rabbit -
特異性
ab24447 reacts with Endothelial lipase. -
アプリケーション
適用あり: IHC-P, ICC/IF, WBmore details -
種交差性
交差種: Mouse, Rat, Sheep, Human, Pig -
免疫原
Synthetic peptide surrounding amino acid 22 of human Endothelial Lipase. (Peptide available as ab53323.)
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特記事項
This product is manufactured by BioVision, an Abcam company and was previously called 3657 Endothelial Lipase Antibody. 3657-100 is the same size as the 100 µg size of ab24447.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24447の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
Use at an assay dependent concentration.
|
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| ICC/IF | (1) |
Use at an assay dependent concentration.
|
| WB |
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 57 kDa.
|
| 特記事項 |
|---|
|
IHC-P
Use at an assay dependent concentration. |
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ICC/IF
Use at an assay dependent concentration. |
|
WB
Use a concentration of 1 - 4 µg/ml. Detects a band of approximately 57 kDa. |
ターゲット情報
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機能
Has phospholipase and triglyceride lipase activities. Hydrolyzes high density lipoproteins (HDL) more efficiently than other lipoproteins. Binds heparin. -
組織特異性
High level of expression in the liver, placenta, lung, thyroid, kidney, testis and in the corpus luteum of the ovary. Expressed also in coronary artery endothelial cells, umbilical vein endothelial cells and in hepatocyte and osteosarcoma cell lines. Not detected in heart, brain and muscle. -
配列類似性
Belongs to the AB hydrolase superfamily. Lipase family.
Contains 1 PLAT domain. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 9388 Human
- Entrez Gene: 16891 Mouse
- Entrez Gene: 291437 Rat
- Omim: 603684 Human
- SwissProt: Q9Y5X9 Human
- SwissProt: Q9WVG5 Mouse
- SwissProt: Q8VBX1 Rat
- Unigene: 465102 Human
see all -
別名
- EDL antibody
- EL antibody
- Endothelial cell-derived lipase antibody
see all
画像
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Western blot - Anti-LIPG antibody (ab24447)Anti-LIPG antibody (ab24447) + HepG2 lysate
Observed band size: 57 kDa why is the actual band size different from the predicted?
Use ab24447 at 1-4µg/ml.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab24447 は 2 報の論文で使用されています。
- Cadenas C et al. LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer. Int J Cancer 145:901-915 (2019). PubMed: 30653260
- Kimura N et al. Multiple endocrine neoplasia type 1-associated cystic pancreatic endocrine neoplasia and multifocal cholesterol granulomas. Pathol Int 60:321-5 (2010). IHC-P ; Human . PubMed: 20403035
