Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR3344(2)] to LHX3/LIM - BSA and Azide free
- Suitable for: Flow Cyt, WB, IP
- Reacts with: Mouse, Rat, Human
製品名Anti-LHX3/LIM antibody [EPR3344(2)] - BSA and Azide free
LHX3/LIM 一次抗体 製品一覧
製品の詳細Rabbit monoclonal [EPR3344(2)] to LHX3/LIM - BSA and Azide free
アプリケーション適用あり: Flow Cyt, WB, IPmore details
適用なし: ICC or IHC-P
種交差性交差種: Mouse, Rat, Human
Synthetic peptide within Human LHX3/LIM aa 300-400. The exact sequence is proprietary.
Ab247966 is the carrier-free version of ab124697. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
ab247966 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
解離定数（KD 値）KD = 6.84 x 10 -11 M Learn more about KD
Concentration information loading...
Our Abpromise guarantee covers the use of ab247966 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use at an assay dependent concentration.|
|WB||Use at an assay dependent concentration. Detects a band of approximately 43 kDa (predicted molecular weight: 43 kDa).|
|IP||Use at an assay dependent concentration.|
機能Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with Pit-1.
関連疾患Defects in LHX3 are the cause of pituitary hormone deficiency combined type 3 (CPHD3) [MIM:221750]; also known as combined pituitary hormone deficiency with rigid cervical spine or sensorineural deafness with pituitary dwarfism. CPHD is characterized by a complete deficit in all but one (adrenocorticotropin) anterior pituitary hormone and a rigid cervical spine leading to limited head rotation.
配列類似性Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding domains.
ドメインThe LIM domain specifically interacts with the Pit-1 POU domain and is required for synergistic interactions with Pit-1, but not for basal transcriptional activation events.
- Information by UniProt
- CPHD 3 antibody
- CPHD3 antibody
- DKFZp762A2013 antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.