製品の概要

  • 製品名

    Levcromakalim, KATP channel activator
  • 製品の詳細

    KATP channel activator
  • 生理活性の詳細

    Powerful smooth muscle relaxant. Acts by direct activation of ATP-sensitive K+ channels. Active enantiomer of cromakalim (ab120486). EC50 = 1.6 μM as measured in rat intracardiac ganglia neurones.
  • 精製度

    > 99%
  • CAS 番号

    94535-50-9
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Brayden JE Functional roles of KATP channels in vascular smooth muscle. Clin Exp Pharmacol Physiol 29:312-6 (2002). Read more (PubMed: 11985542) »
  • Hogg RC & Adams DJ An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia. J Physiol 534:713-20 (2001). Read more (PubMed: 11483702) »
  • Bowring NE  et al. Comparison of the airways relaxant and hypotensive potencies of the potassium channel activators BRL 55834 and levcromakalim (BRL 38227) in vivo in guinea-pigs and rats. Br J Pharmacol 109:1133-9 (1993). Read more (PubMed: 8401925) »
  • Taylor SG  et al. The inhibitory effects of cromakalim and its active enantiomer BRL 38227 against various agonists in guinea pig and human airways: comparison with pinacidil and verapamil. J Pharmacol Exp Ther 261:429-37 (1992). Read more (PubMed: 1578358) »

レビューと Q&A

Answer

Thank you for your enquiry.

As far as I am aware from our records, there should be no import restrictions and cromakalim[ab120486], and lev cromakalim [ab120485] are available in India.

As we do not sell direct in India, for price and confirmation of availability I can recommend to contact one of our following official distributors in India:

Allied Scientific Products
39/19B Gopal Nagar Road
Kolkata-700027
India

Website: http://www.alliedscientific.net
Freephone: 1800 345 7777
Fax: +91 33 24566683 / 24790626
Tel: +91 33 24566684/24793109/9039


NuLife Consultants & Distributors (Pvt.) Ltd.
NuLife Consultants & Distributors (Pvt.) Ltd.
M-52, First Floor,
Lajpat Nagar- Part-II,
New Delhi-110024-India

Tel: 011-46112691/ 46112692/ 29836141
Website: http://www.nulife.in
Fax: 91 - 011-46586216
Email: nulife@bol.net.in
sales@nulife.in

I hope this information will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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