Key features and details
- Rat monoclonal [MEC5] to Laminin
- Suitable for: IHC-Fr
- Reacts with: Mouse, Rat, Human
- Isotype: IgG1
製品名Anti-Laminin antibody [MEC5]
Laminin 一次抗体 製品一覧
製品の詳細Rat monoclonal [MEC5] to Laminin
特異性This antibody reacts with the P1 fragment of laminin.
アプリケーション適用あり: IHC-Frmore details
種交差性交差種: Mouse, Rat, Human
Full length native protein (purified) corresponding to Rat Laminin. ab2466 was derived from DZB rats that had developed membranous glomerulopathy upon exposure to mercuric chloride
保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Concentration information loading...
精製度Tissue culture supernatant
Our Abpromise guarantee covers the use of ab2466 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
A pepsin pretreatment is required. Especially useful for immunohistochemical detection of laminin in extracellular matrix or basement membranes in freshly frozen tissue sections of rat, mouse or humans.
機能Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
組織特異性Broadly expressed in: skin, heart, lung, and the reproductive tracts.
配列類似性Contains 11 laminin EGF-like domains.
Contains 1 laminin IV type A domain.
Contains 1 laminin N-terminal domain.
ドメインThe alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
Domain IV is globular.
細胞内局在Secreted > extracellular space > extracellular matrix > basement membrane.
- Information by UniProt
- LAMA 1 antibody
- LAMA antibody
- LAMA1 antibody
ab2466 は 2 報の論文で使用されています。
- Berthod F et al. Spontaneous fibroblast-derived pericyte recruitment in a human tissue-engineered angiogenesis model in vitro. J Cell Physiol 227:2130-7 (2012). IHC-Fr ; Human . PubMed: 21769871
- Aten J et al. Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy. Am J Pathol 146:1467-80 (1995). PubMed: 7778685