Key features and details
- Rat monoclonal [MEC5] to Laminin
- Reacts with: Mouse, Rat, Human
- Isotype: IgG1
製品名Anti-Laminin antibody [MEC5]
Laminin 一次抗体 製品一覧
製品の詳細Rat monoclonal [MEC5] to Laminin
特異性This antibody reacts with the P1 fragment of laminin.
種交差性交差種: Mouse, Rat, Human
Full length native protein (purified) corresponding to Rat Laminin. ab2466 was derived from DZB rats that had developed membranous glomerulopathy upon exposure to mercuric chloride
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Concentration information loading...
精製度Tissue culture supernatant
機能Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
組織特異性Broadly expressed in: skin, heart, lung, and the reproductive tracts.
配列類似性Contains 11 laminin EGF-like domains.
Contains 1 laminin IV type A domain.
Contains 1 laminin N-terminal domain.
ドメインThe alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
Domain IV is globular.
細胞内局在Secreted > extracellular space > extracellular matrix > basement membrane.
- Information by UniProt
- LAMA 1 antibody
- LAMA antibody
- LAMA1 antibody
ab2466 は 2 報の論文で使用されています。
- Berthod F et al. Spontaneous fibroblast-derived pericyte recruitment in a human tissue-engineered angiogenesis model in vitro. J Cell Physiol 227:2130-7 (2012). IHC-Fr ; Human . PubMed: 21769871
- Aten J et al. Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy. Am J Pathol 146:1467-80 (1995). PubMed: 7778685