Key features and details
- Rabbit polyclonal to Lambda Light chain (FITC)
- Reacts with: Human
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG
製品名Anti-Lambda Light chain antibody (FITC)
Lambda Light chain 一次抗体 製品一覧
製品の詳細Rabbit polyclonal to Lambda Light chain (FITC)
標識FITC. Ex: 493nm, Em: 528nm
Pool of human Lambda light chain isolated from the urine of patients with Bence Jones Proteinuria.
Fluorescein isothiocyanate (FITC) isomer 1.
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保存方法Shipped at 4°C. Store at +4°C.
バッファーPreservative: 0.05% Sodium azide
Constituent: 1% BSA
Concentration information loading...
特記事項（精製）Traces of contaminating antibodies have been removed by solid phase absorption. Only the lambda precipitation line appeared in cross immunoelectrophoresis.
Not tested in other applications.
Optimal dilutions / concentrations should be determined by the end user.
関連性All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of Kappa to Lambda is 70:30 , the vast majority of which is bound to heavy-chain in immunoglobulin. In normal individuals low levels of free light-chain arepresent in serum (kappa, 1.6-15.2 mg/L; Lambda, 0.4-4.2mg/L), with the occurrence of multiple myeloma or other B-cell malignancies these levels can be greatly elevated and can be found at high levels in the urine (Bence-Jones proteins).
- Bence Jones protein antibody
- BJP antibody
- Constant region of lambda light chains antibody