Anti-Kv1.4/RK3 抗体 (ab16718)
Key features and details
- Rabbit polyclonal to Kv1.4/RK3
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
製品の概要
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製品名
Anti-Kv1.4/RK3 antibody
Kv1.4/RK3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Kv1.4/RK3 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human
交差が予測される動物種: Mouse, Cow
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免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.08% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Ammonium Sulphate Precipitation -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16718の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (1) |
Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 73 kDa. Detects a band of approximately 76 KDa in HEK293 lysate and 90 kDa in rat hippocampal membranes.
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| 特記事項 |
|---|
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WB
Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 73 kDa. Detects a band of approximately 76 KDa in HEK293 lysate and 90 kDa in rat hippocampal membranes. |
ターゲット情報
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機能
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. -
配列類似性
Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.4/KCNA4 sub-subfamily. -
ドメイン
The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 281880 Cow
- Entrez Gene: 3739 Human
- Entrez Gene: 16492 Mouse
- Entrez Gene: 25469 Rat
- Omim: 176266 Human
- SwissProt: Q05037 Cow
- SwissProt: P22459 Human
- SwissProt: Q61423 Mouse
see all -
別名
- Voltage gated K+ channel HuKII antibody
- Fetal skeletal muscle potassium channel antibody
- HBK4 antibody
see all
画像
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Western blot - Anti-Kv1.4/RK3 antibody (ab16718)
Western blots using ab16718.
1: HEK293 cells transfected with Kv1.4/RK3.
2: Rat hippocampal membrane.
The size difference observed can probably be explained by differential post-translational processing.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab16718 は 2 報の論文で使用されています。
- Ying-Wang et al. The Beneficial Effects of Electroacupuncture at PC6 Acupoints (Neiguan) on Myocardial Ischemia in ASIC3 -/- mice. J Acupunct Meridian Stud 11:88-96 (2018). WB . PubMed: 29608997
- Cho JH et al. Reverse electrical remodeling in rats with heart failure and preserved ejection fraction. JCI Insight 3:N/A (2018). PubMed: 30282820
