Anti-KSHV ORF8 抗体 (ab36599)
Key features and details
- Rabbit polyclonal to KSHV ORF8
- Suitable for: WB
- Reacts with: Human herpesvirus 8
- Isotype: IgG
製品の概要
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製品名
Anti-KSHV ORF8 antibody -
製品の詳細
Rabbit polyclonal to KSHV ORF8 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human herpesvirus 8 -
免疫原
Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
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ポジティブ・コントロール
- TPA-induced BCBL-1 cell lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Ammonium Sulphate Precipitation -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab36599の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/1000. Detects a band of approximately 68 kDa.
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特記事項 |
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WB
1/500 - 1/1000. Detects a band of approximately 68 kDa. |
ターゲット情報
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関連性
Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells. -
別名
- HHV 8 antibody
- Human herpesvirus 8 antibody
- Kaposi's sarcoma herpes virus antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (2)
ab36599 は 2 報の論文で使用されています。
- Wang X et al. Male hormones activate EphA2 to facilitate Kaposi's sarcoma-associated herpesvirus infection: Implications for gender disparity in Kaposi's sarcoma. PLoS Pathog 13:e1006580 (2017). PubMed: 28957431
- Lin X et al. MicroRNAs and unusual small RNAs discovered in Kaposi's sarcoma-associated herpesvirus virions. J Virol 86:12717-30 (2012). PubMed: 22973026