Anti-Kif2a 抗体 (ab3475)

Submit a review Q&A (2)

Key features and details

  • Rabbit polyclonal to Kif2a
  • Suitable for: WB
  • Reacts with: Mouse
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-Kif2a antibody
    Kif2a 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to Kif2a

  • 由来種

    Rabbit

  • 特異性

    Detects Kinesin 2 (Kif2a) from mouse tissues.

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Mouse
    交差が予測される動物種: Rat, Chicken, Cow, Human, Xenopus laevis

  • 免疫原

    Synthetic peptide corresponding to Mouse Kif2a aa 1-11.
    Sequence:

    MVTSLNEDNES


    (Peptide available as ab4992)

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI

  • ポジティブ･コントロール

    • Mouse brain homogenate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab3475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/200. Detects a band of approximately 95 kDa (predicted molecular weight: 79 kDa).Can be blocked with KLC1 peptide (ab4992).

This antibody detects a ~95 kDa protein representing KIF 2 from mouse brain homogenate.

ターゲット情報

  • 機能

    Plus end-directed microtubule-dependent motor required for normal brain development. May regulate microtubule dynamics during axonal growth. Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate. Required for normal spindle dynamics during mitosis. Promotes spindle turnover. Implicated in formation of bipolar mitotic spindles. Has microtubule depolymerization activity.

  • 配列類似性

    Belongs to the kinesin-like protein family. MCAK/KIF2 subfamily.
    Contains 1 kinesin-motor domain.

  • 細胞内局在

    Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton > spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1.
  • Information by UniProt

  • 参照データベース

    see all

  • 別名

    • CDCBM3 antibody
    • HK2 antibody
    • KIF2 antibody
    • KIF2A antibody
    • KIF2A_HUMAN antibody
    • Kinesin 2 antibody
    • Kinesin heavy chain 2 antibody
    • Kinesin heavy chain member 2 antibody
    • Kinesin heavy chain member 2A antibody
    • Kinesin like protein KIF2A antibody
    • Kinesin-2 antibody
    • Kinesin-like protein KIF2A antibody
    • KNS2 antibody
    • M Kinesin antibody
    see all

参考文献 (0)

ab3475 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab3475 は論文での使用が確認できていません。

レビューと Q&A

Show All レビュー Q&A
レビューを送る 質問を送る

1-2 of 2 Abreviews or Q&A

Question

 Dear technical Team, Could you please tell us if article AB3475 Anti SatB2 :  Does this article can be used on formadldehyde fixed(prepared material).  Kind regards,    

Read More
Answer

Thank you for contacting us and for your interest in our products. I am sorry to confirm that as far as we are aware, ab3475 Kif2a antibody has not been tested in IHC-P.  All tested and guaranteed applications and species are specified on our datasheets, and these are updated as soon as any new information is brought to our attention. I can suggest to consider the following antibody, which has been tested in human and IHC-P ab55383 Mouse monoclonal Anti-Kif2a antibody Tested in:  IHC-P, WB              Reacts with:  Hu  Click here (or use the following: https://www.abcam.com/index.html?datasheet=55383).  If you would like to test the ab3475 in IHC-P, please contact me again prior to the purchase by replying to this message as you may be eligible for our testing discount program. Otherwise, we like to encourage all of our customers to submit an Abreview via the online product datasheet. We always appreciate customer feedback, whether positive or negative, and we make all product information available to researchers. Plus, each Abreview earns Abpoints that can be used for discounts on future purchases or rewards such as Amazon.com gift certificates. To find out more about our Abreview system, please see the following link: https://www.abcam.com/abreviews I hope this information is helpful. Please do not hesitate to contact me for any further advice or information.    

Read More

Question

I thought I would point out to you that there is confusion in your antibody terminology: the kinesin 2 antibody is actually against KIF2, which is NOT kinesin 2 (or II)! It should be called anti-KIF2, since that's what it is!

Read More
Answer

Thank you for your comment. We will update and change the name of this antibody shortly. The name will be: Kinesin, Heavy Chain, 2 (KIF2).

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com