Key features and details
- Goat polyclonal to JIP3
- Suitable for: IHC-P
- Reacts with: Mouse
- Isotype: IgG
JIP3 一次抗体 製品一覧
製品の詳細Goat polyclonal to JIP3
特異性This antibody is expected to recognise both human isoforms of this protein.
アプリケーション適用あり: IHC-Pmore details
交差が予測される動物種: Rat, Cow, Human
特記事項GenBank Accession Number – NP_055948; NP_203750. LocusLink ID - 23162 (human); 30957 (mouse). Gene Ontology terms - vesicle-mediated transport; kinesin complex; cytoplasm; kinesin binding; MAP-kinase scaffold activity; protein kinase binding; regulation of JNK cascade.
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA
Concentration information loading...
精製度Immunogen affinity purified
特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Our Abpromise guarantee covers the use of ab4545 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
機能The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interations with the JNK-signaling components and motor proteins.
配列類似性Belongs to the JIP scaffold family.
翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
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