Isradipine, L-type Ca2+ channel blocker (ab120142)
Key features and details
- L-type Ca2+ channel blocker
- CAS Number: 75695-93-1
- Soluble in DMSO to 100 mM and in ethanol to 50 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Isradipine, L-type Ca2+ channel blocker -
製品の詳細
L-type Ca2+ channel blocker -
生理活性の詳細
L-type Ca2+ channel blocker.
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CAS 番号
75695-93-1 -
構造式
製品の特性
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体系名
4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester -
分子量
371.39 -
分子式
C19H21N3O5 -
PubChem 登録番号
3784 -
保存方法
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in DMSO to 100 mM and in ethanol to 50 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
O=C(OC)C3=C(C)NC(C)=C(C(=O)OC(C)C)C3c1cccc2nonc12 -
由来
Synthetic
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研究分野
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipases
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab120142 は 3 報の論文で使用されています。
- Meyer DJ et al. The Na+/K+ pump dominates control of glycolysis in hippocampal dentate granule cells. Elife 11:N/A (2022). PubMed: 36222651
- Díaz-García CM et al. The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle. Elife 10:N/A (2021). PubMed: 33555254
- Jurkovicová-Tarabová B et al. Repertoire of high voltage-activated Ca2+ channels in the lateral superior olive: functional analysis in wild-type, Ca(v)1.3(-/-), and Ca(v)1.2DHP(-/-) mice. J Neurophysiol 108:365-79 (2012). PubMed: 22539826