Anti-IP10 抗体 (ab9807)
Key features and details
- Rabbit polyclonal to IP10
- Suitable for: WB, Sandwich ELISA
- Reacts with: Rat, Human, Recombinant fragment
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-IP10 antibody
IP10 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IP10 -
由来種
Rabbit -
アプリケーション
適用あり: WB, Sandwich ELISAmore details -
種交差性
交差種: Rat, Human, Recombinant fragment -
免疫原
Recombinant full length protein corresponding to Human IP10. Highly pure (>98%) recombinant hIP-10 (human Interferon Inducible Protein 10)
Database link: P02778 -
ポジティブ･コントロール
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特記事項
Although some customers have been successful in IHC we no longer batch test in this application.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200µl of sterile water. -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
バッファー
No preservative, sterile filtered -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab9807の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use at an assay dependent concentration. To detect hIP-10 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIP-10 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
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| Sandwich ELISA |
Use at an assay dependent concentration.
To detect hIP-10 by direct ELISA (using 100 µl/well antibody solution) a concentration of 0.5 - 2.0 µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with biotinylated anti-IP10 antibody (ab271283), allows the detection of 0.2 - 0.4 ng/well of recombinant hIP-10. |
| 特記事項 |
|---|
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WB
Use at an assay dependent concentration. To detect hIP-10 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIP-10 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. |
|
Sandwich ELISA
Use at an assay dependent concentration. To detect hIP-10 by direct ELISA (using 100 µl/well antibody solution) a concentration of 0.5 - 2.0 µg/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with biotinylated anti-IP10 antibody (ab271283), allows the detection of 0.2 - 0.4 ng/well of recombinant hIP-10. |
ターゲット情報
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機能
Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. -
配列類似性
Belongs to the intercrine alpha (chemokine CxC) family. -
翻訳後修飾
CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 3627 Human
- Entrez Gene: 245920 Rat
- Omim: 147310 Human
- SwissProt: P02778 Human
- SwissProt: P48973 Rat
- Unigene: 632586 Human
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別名
- Interferon gamma induced factor MOB1, mouse, homolog of antibody
- Interferon gamma induced protein 10 antibody
- 10 kDa interferon gamma induced protein antibody
see all
画像
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Western blot - Anti-IP10 antibody (ab9807)
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Sandwich ELISA - Anti-IP10 antibody (ab9807)ab9807 detecting IP-10 by sandwich ELISA.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (28)
ab9807 は 28 報の論文で使用されています。
- El-Domyati M et al. Systemic CXCL10 is a predictive biomarker of vitiligo lesional skin infiltration, PUVA, NB-UVB and corticosteroid treatment response and outcome. Arch Dermatol Res N/A:N/A (2021). PubMed: 33866437
- Zhan X et al. Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex-mediated STAT1 downregulation. J Exp Med 217:N/A (2020). PubMed: 32181805
- Calvo-Flores Guzmán B et al. The Interplay Between Beta-Amyloid 1-42 (Aß1-42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits. Front Mol Neurosci 13:522073 (2020). PubMed: 33224025
- Viau A et al. Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease. J Am Soc Nephrol 31:1035-1049 (2020). PubMed: 32238474
- Victorelli S et al. Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction. EMBO J 38:e101982 (2019). PubMed: 31633821