製品の概要

  • 製品名
    Anti-Interferon beta antibody [7F-D3]
    Interferon beta 一次抗体 製品一覧
  • 製品の詳細
    Rat monoclonal [7F-D3] to Interferon beta
  • 由来種
    Rat
  • 特異性
    This antibody cross react with IFN beta, but not alpha or gamma.
  • アプリケーション
    適用あり: WB, ELISA, Flow Cyt, Neutralisingmore details
  • 種交差性
    交差種: Mouse
    非交差種: Human
  • 免疫原

    Purified mouse interferon beta.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab24324 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Flow Cyt Use a concentration of 10 µg/ml. PubMed: 24474800

ab18407 - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.

 

Neutralising Use at an assay dependent concentration. At a concentration of 3.6 ng/ml, this antibody neutralizes 10 U/ml of mouse IFN-b to 1 U/ml.

ターゲット情報

  • 機能
    Has antiviral, antibacterial and anticancer activities.
  • 配列類似性
    Belongs to the alpha/beta interferon family.
  • 細胞内局在
    Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • beta-interferon antibody
    • Fibroblast interferon antibody
    • IFB antibody
    • IFF antibody
    • IFN beta antibody
    • IFN-beta antibody
    • IFNB 1 antibody
    • IFNB antibody
    • IFNB_HUMAN antibody
    • IFNB1 antibody
    • Interferon beta 1 fibroblast antibody
    • Interferon beta antibody
    • Interferon beta precursor antibody
    • MGC96956 antibody
    see all

参考文献

This product has been referenced in:
  • Kerur N  et al. cGAS drives noncanonical-inflammasome activation in age-related macular degeneration. Nat Med 24:50-61 (2018). Read more (PubMed: 29176737) »
  • Moore EC  et al. Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms. Oncoimmunology 7:e1404216 (2018). Read more (PubMed: 29900037) »
See all 11 Publications for this product

レビューと Q&A

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1-2 of 2 Abreviews

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Western blot
Sample
Mouse Recombinant protein (recombinant IFNbeta AND mouse hepatocyte lysate)
Loading amount
0.5 µg
Specification
recombinant IFNbeta AND mouse hepatocyte lysate
Gel Running Conditions
Reduced Denaturing (10% SDS-PAGE)
Blocking step
50:50 PBS:Odyssey Blocking Buffer, Li-Cor 927-40100 as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 50% · Temperature: 24°C

Abcam user community

Verified customer

投稿 Aug 28 2012

Abcam has not validated the combination of species/application used in this Abreview.
Application
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample
Mouse Tissue sections (eye tissue)
Specification
eye tissue
Fixative
Paraformaldehyde
Antigen retrieval step
Heat mediated
Permeabilization
No

Abcam user community

Verified customer

投稿 Apr 20 2011

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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