Anti-Integrin alpha 3 抗体 (ab133198)
Key features and details
- Rabbit polyclonal to Integrin alpha 3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Integrin alpha 3 antibody
Integrin alpha 3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Integrin alpha 3 -
由来種
Rabbit -
特異性
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rabbit, Horse, Hamster, Cow, Dog, Monkey, Gorilla, Opossum, Common marmoset, Bat, Elephant -
免疫原
18 amino acid synthetic peptide from the N-terminus of Human Integrin alpha 3.
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ポジティブ・コントロール
- Human skin and colon smooth muscle tissues.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. -
バッファー
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab133198の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
Use a concentration of 7.5 - 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
Use a concentration of 7.5 - 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. -
組織特異性
Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells. -
配列類似性
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. -
翻訳後修飾
Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 100386753 Common marmoset
- Entrez Gene: 508490 Cow
- Entrez Gene: 491074 Dog
- Entrez Gene: 100056202 Horse
- Entrez Gene: 3675 Human
- Entrez Gene: 16400 Mouse
- Omim: 605025 Human
- SwissProt: F1MMS9 Cow
see all -
別名
- AA407068 antibody
- Antigen identified by monoclonal antibody J143 antibody
- CD49 antigen like family member C antibody
see all
画像
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Immunohistochemical analysis of paraffin-embedded, formalin-fixed Human skin tissue labelling Integrin alpha 3 with ab133198 at 10 µg/ml,
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Immunohistochemical analysis of paraffin-embedded, formalin-fixed Human colon, smooth muscle, tissue labelling Integrin alpha 3 with ab133198 at 10 µg/ml, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab133198 は論文での使用が確認できていません。