Anti-IL-13 receptor alpha 2 抗体 (ab108534)
Key features and details
- Rabbit polyclonal to IL-13 receptor alpha 2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-IL-13 receptor alpha 2 antibody
IL-13 receptor alpha 2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to IL-13 receptor alpha 2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat
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免疫原
Recombinant fragment corresponding to Human IL-13 receptor alpha 2 aa 72-349.
Database link: BC020739 -
ポジティブ･コントロール
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.02% Sodium azide -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab108534の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | (2) |
1/500 - 1/1000. Predicted molecular weight: 44 kDa.
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| IHC-P |
1/100 - 1/500.
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| 特記事項 |
|---|
|
WB
1/500 - 1/1000. Predicted molecular weight: 44 kDa. |
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IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). -
配列類似性
Belongs to the type I cytokine receptor family. Type 5 subfamily.
Contains 1 fibronectin type-III domain. -
ドメイン
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 3598 Human
- Entrez Gene: 16165 Mouse
- Entrez Gene: 171060 Rat
- Omim: 300130 Human
- SwissProt: Q14627 Human
- SwissProt: O88786 Mouse
- SwissProt: Q8VHK6 Rat
- Unigene: 336046 Human
see all -
別名
- Cancer/testis antigen 19 antibody
- CD213a2 antibody
- CT19 antibody
see all
画像
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Western blot - Anti-IL-13 receptor alpha 2 antibody (ab108534)Anti-IL-13 receptor alpha 2 antibody (ab108534) at 1/500 dilution + Human fetal liver lysate
Predicted band size: 44 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL-13 receptor alpha 2 antibody (ab108534)Membrane staining of IL13 receptor alpha 2 in formalin-fixed, paraffin-embedded Human fetal liver tissue with 1/100 ab108534.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab108534 は 1 報の論文で使用されています。
- Li L et al. M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Ra2/MAPK Pathway in Rat Intervertebral Disc Degeneration. Front Immunol 12:666361 (2021). PubMed: 34168643