Anti-IL-11 抗体 [EPR15253] (ab187167)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR15253] to IL-11
- Suitable for: WB
- Reacts with: Rat, Human
Related conjugates and formulations
製品の概要
-
製品名
Anti-IL-11 antibody [EPR15253]
IL-11 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR15253] to IL-11 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat, Human -
免疫原
Recombinant fragment. This information is proprietary to Abcam and/or its suppliers.
-
ポジティブ・コントロール
- Active IL-11 full length recombinant protein; Rat plasma lysate.
-
特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR15253 -
アイソタイプ
IgG -
研究分野
関連製品
-
Alternative Versions
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab187167の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000 - 1/2000. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa).
|
特記事項 |
---|
WB
1/1000 - 1/2000. Detects a band of approximately 25 kDa (predicted molecular weight: 21 kDa). |
ターゲット情報
-
機能
Directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. -
配列類似性
Belongs to the IL-6 superfamily. -
細胞内局在
Secreted. - Information by UniProt
-
参照データベース
- Entrez Gene: 3589 Human
- Entrez Gene: 171040 Rat
- Omim: 147681 Human
- SwissProt: P20809 Human
- SwissProt: Q99MF5 Rat
- Unigene: 467304 Human
- Unigene: 198483 Rat
-
別名
- Adipogenesis inhibitory factor antibody
- AGIF antibody
- IL 11 antibody
see all
画像
-
Anti-IL-11 antibody [EPR15253] (ab187167) at 1/1000 dilution + Rat plasma lysate at 10 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 21 kDa -
Anti-IL-11 antibody [EPR15253] (ab187167) at 1/2000 dilution + Recombinant human IL-11 protein (ab9553) at 0.01 µg
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 21 kDa
データシートおよび資料
-
SDS download
-
Datasheet download
Certificate of Compliance
参考文献 (4)
ab187167 は 4 報の論文で使用されています。
- Xu YL et al. Long non-coding RNA CASC7 is associated with the pathogenesis of heart failure via modulating the expression of miR-30c. J Cell Mol Med 24:11500-11511 (2020). PubMed: 32860492
- Feng Q et al. Denosumab inhibits MCF-7 cell line-induced spontaneous osteoclastogenesis via the RANKL/MALAT1/miR-124 axis. Transl Cancer Res 9:2482-2491 (2020). PubMed: 35117607
- Tan HS et al. KRT8 upregulation promotes tumor metastasis and is predictive of a poor prognosis in clear cell renal cell carcinoma. Oncotarget 8:76189-76203 (2017). PubMed: 29100303
- Zheng H et al. TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling. Sci Rep 6:37070 (2016). WB ; Human . PubMed: 27901021