製品の概要

  • 製品名

  • 製品の詳細

    Rabbit polyclonal to ICAD
  • 由来種

    Rabbit
  • アプリケーション

    適用あり: IHC-FrFl, WBmore details
  • 種交差性

    交差種: Mouse
  • 免疫原

    Synthetic peptide, corresponding to amino acids 312-331 of Mouse ICAD (CT).

  • ポジティブ・コントロール

    • Mouse lung tissue lysate.
  • 特記事項

    Stable for one year.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab2040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-FrFl Use a concentration of 5 µg/ml.
WB 1/500 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

ターゲット情報

  • 機能

    Inhibitor of the caspase-activated DNase (DFF40).
  • 配列類似性

    Contains 1 CIDE-N domain.
  • 翻訳後修飾

    Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在

    Cytoplasm.
  • Information by UniProt
  • 参照データベース

  • 別名

    • A330085O09Rik antibody
    • Caspase activated deoxyribonuclease inhibitor short form antibody
    • DFF 1 antibody
    • DFF 45 antibody
    • DFF alpha antibody
    • DFF-45 antibody
    • DFF1 antibody
    • DFF35 antibody
    • DFF45 antibody
    • DFFA antibody
    • Dffa DNA fragmentation factor, alpha subunit antibody
    • DFFA_HUMAN antibody
    • DNA fragmentation factor 45 kDa subunit antibody
    • DNA Fragmentation Factor Alpha Subunit antibody
    • DNA fragmentation factor subunit alpha antibody
    • DNA fragmentation factor, 45 kD, alpha subunit antibody
    • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibody
    • DNA fragmentation factor, 45kDa, alpha polypeptide antibody
    • DNA fragmentation factor, alpha subunit antibody
    • DNAation factor 45 kDa subunit antibody
    • H13 antibody
    • ICAD antibody
    • ICAD L antibody
    • ICAD S antibody
    • Inhibitor of CAD antibody
    • Inhibitor of Caspase Activated DNase antibody
    • MGC143066 antibody
    • OTTHUMP00000001903 antibody
    • OTTHUMP00000001904 antibody
    • RP23 121D17.3 antibody
    see all

画像

  • Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse kidney tissue labeling ICAD with Anti-ICAD antibody (ab2040) at 5μg/ml.
  • Western blot analysis of ICAD in murine lung (L), brain (B), liver (L), and kidney tissue lysate with anti-ICAD (CT) at 1/1000 dilution.

プロトコール

参考文献

This product has been referenced in:

  • Meram AT  et al. Hydrogen Sulfide Is Increased in Oral Squamous Cell Carcinoma Compared to Adjacent Benign Oral Mucosae. Anticancer Res 38:3843-3852 (2018). Read more (PubMed: 29970504) »
See 1 Publication for this product

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