Anti-ICAD 抗体 (ab2040)

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Key features and details

  • Rabbit polyclonal to ICAD
  • Suitable for: IHC-P, WB
  • Reacts with: Mouse
  • Isotype: IgG

製品の概要

  • 製品名

    Anti-ICAD antibody
    ICAD 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to ICAD

  • 由来種

    Rabbit

  • アプリケーション

    適用あり: IHC-P, WBmore details

  • 種交差性

    交差種: Mouse

  • 免疫原

    Synthetic peptide, corresponding to amino acids 312-331 of Mouse ICAD (CT).

  • ポジティブ･コントロール

    • Mouse lung tissue lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab2040 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
WB 1/500 - 1/2000. Detects a band of approximately 45 kDa (predicted molecular weight: 45 kDa).

ターゲット情報

  • 機能

    Inhibitor of the caspase-activated DNase (DFF40).

  • 配列類似性

    Contains 1 CIDE-N domain.

  • 翻訳後修飾

    Caspase-3 cleaves DFF45 at 2 sites to generate an active factor.
    Phosphorylated upon DNA damage, probably by ATM or ATR.

  • 細胞内局在

    Cytoplasm.
  • Information by UniProt

  • 参照データベース

    • 別名

      • A330085O09Rik antibody
      • Caspase activated deoxyribonuclease inhibitor short form antibody
      • DFF 1 antibody
      • DFF 45 antibody
      • DFF alpha antibody
      • DFF-45 antibody
      • DFF1 antibody
      • DFF35 antibody
      • DFF45 antibody
      • DFFA antibody
      • Dffa DNA fragmentation factor, alpha subunit antibody
      • DFFA_HUMAN antibody
      • DNA fragmentation factor 45 kDa subunit antibody
      • DNA Fragmentation Factor Alpha Subunit antibody
      • DNA fragmentation factor subunit alpha antibody
      • DNA fragmentation factor, 45 kD, alpha subunit antibody
      • DNA fragmentation factor, 45kDa, alpha polypeptide (DFFA), transcript variant 1 antibody
      • DNA fragmentation factor, 45kDa, alpha polypeptide antibody
      • DNA fragmentation factor, alpha subunit antibody
      • DNAation factor 45 kDa subunit antibody
      • H13 antibody
      • ICAD antibody
      • ICAD L antibody
      • ICAD S antibody
      • Inhibitor of CAD antibody
      • Inhibitor of Caspase Activated DNase antibody
      • MGC143066 antibody
      • OTTHUMP00000001903 antibody
      • OTTHUMP00000001904 antibody
      • RP23 121D17.3 antibody
      see all

    画像

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAD antibody (ab2040)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ICAD antibody (ab2040)

      Immunohistochemistry (Formalin-fixed paraffin embedded sections) of mouse kidney tissue labeling ICAD with Anti-ICAD antibody (ab2040) at 5µg/ml.

    • Western blot - Anti-ICAD antibody (ab2040)
      Western blot - Anti-ICAD antibody (ab2040)

      Western blot analysis of ICAD in murine lung (L), brain (B), liver (L), and kidney tissue lysate with anti-ICAD (CT) at 1/1000 dilution.

    参考文献 (1)

    ab2040 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab2040 は 1 報の論文で使用されています。

    • Meram AT  et al. Hydrogen Sulfide Is Increased in Oral Squamous Cell Carcinoma Compared to Adjacent Benign Oral Mucosae. Anticancer Res 38:3843-3852 (2018). PubMed: 29970504

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