Human UCP1 peptide (ab24282)
Key features and details
- Expression system: Synthetic
- Purity: > 90% HPLC
- Suitable for: Blocking
製品の詳細
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製品名
Human UCP1 peptide
UCP1 タンパク質・ペプチド 製品一覧 -
精製度
> 90 % HPLC. -
発現系
Synthetic -
アクセッション番号
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Animal free
No -
由来
Synthetic -
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生物種
Human -
配列の追加情報
Synthetic peptide corresponding to Human UCP1 aa 100-200, the exact sequence is proprietary information.
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関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab24282 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-UCP1 antibody (ab23841)
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製品の状態
Liquid -
備考
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use. -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Information available upon request.
関連情報
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別名
- mitochondrial brown fat uncoupling protein
- Mitochondrial brown fat uncoupling protein 1
- SLC25A7
see all -
機能
UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. -
組織特異性
Brown adipose tissue. -
配列類似性
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats. -
細胞内局在
Mitochondrion inner membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (2)
ab24282 は 2 報の論文で使用されています。
- Kawashima M et al. Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells. Cancer Metab 8:13 (2020). PubMed: 32647572
- Pearson LE et al. To each its own: Thermoregulatory strategy varies among neonatal polar phocids. Comp Biochem Physiol A Mol Integr Physiol 178:59-67 (2014). Blocking . PubMed: 25151642
