Anti-Human placental lactogen (epitope 2) 抗体 [INN-hPL-37] (ab11396)
Key features and details
- Mouse monoclonal [INN-hPL-37] to Human placental lactogen (epitope 2)
- Suitable for: RIA
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Human placental lactogen (epitope 2) antibody [INN-hPL-37] -
製品の詳細
Mouse monoclonal [INN-hPL-37] to Human placental lactogen (epitope 2) -
由来種
Mouse -
特異性
Radioimmunological direct binding studies were performed with 125I-labelled. hPL, hGH, hPRL and increasing amounts of INN-hPL-37. In addition, competitive RIA with unlabelled hGH, hPRL and hPL were used for characterization. In competitive RIA cross reactivity with hGH and hPRL was below 1%. Direct binding demonstrated 39% reactivity with hGH but no cross reactivity with hPRL. -
アプリケーション
適用あり: RIAmore details -
種交差性
交差種: Human -
免疫原
Other Immunogen Type corresponding to Human Human placental lactogen (epitope 2).
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特記事項
This product should be stored undiluted. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Preservative: 0.09% Sodium azide -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
Purification by affinity chromatography. -
ポリ/モノ
モノクローナル -
クローン名
INN-hPL-37 -
ミエローマ
x63-Ag8.653 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab11396の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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RIA |
Use at an assay dependent concentration.
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特記事項 |
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RIA
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Placental lactogen is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 1442 Human
- Entrez Gene: 1443 Human
- Omim: 150200 Human
- SwissProt: P01243 Human
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別名
- choriomammotropin antibody
- Chorionic somatomammotropin A antibody
- Chorionic somatomammotropin hormone 1 (placental lactogen) antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (1)
ab11396 は 1 報の論文で使用されています。
- Jin F et al. Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis. Int J Mol Med 37:949-57 (2016). IF . PubMed: 26935516