Anti-Human IgG4 heavy chain 抗体 [5C7] (ab1930)
Key features and details
- Mouse monoclonal [5C7] to Human IgG4 heavy chain
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Human IgG4 heavy chain antibody [5C7] -
製品の詳細
Mouse monoclonal [5C7] to Human IgG4 heavy chain -
由来種
Mouse -
特異性
Subclass-specific for human IgG4. No allotype restriction. Fc-region specific. -
種交差性
交差種: Human -
免疫原
IgG4 from human serum.
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特記事項
Concentration varies from lot to lot and can be provided on request.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Protein A purified -
特記事項（精製）
Chromatography on protein A Sepharose -
ポリ/モノ
モノクローナル -
クローン名
5C7 -
ミエローマ
Sp2/0 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
ターゲット情報
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関連性
Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants. -
細胞内局在
Secreted -
参照データベース
- Entrez Gene: 3503 Human
- Omim: 147130 Human
- SwissProt: P01861 Human
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別名
- AU044919 antibody
- Gamma 2b immunoglobulin antibody
- Ig gamma 4 chain C region antibody
see all
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab1930 は 2 報の論文で使用されています。
- Harlow DE et al. Myelin Proteolipid Protein Complexes with av Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. J Neurosci 35:12018-32 (2015). PubMed: 26311781
- Medeiros MM et al. Natural antibody response to Plasmodium falciparum merozoite antigens MSP5, MSP9 and EBA175 is associated to clinical protection in the Brazilian Amazon. BMC Infect Dis 13:608 (2013). ELISA ; Human . PubMed: 24373342