Key features and details
- Purity: > 70% HPLC
製品名Human Asialoglycoprotein Receptor 1/HL-1 peptide
Asialoglycoprotein Receptor 1/HL-1 タンパク質・ペプチド 製品一覧
精製度> 70 % HPLC.
70 - 90% by HPLC
Our Abpromise guarantee covers the use of ab98248 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
Previously labelled as Asialoglycoprotein Receptor 1.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Information available upon request.
- ASGP-R 1
- ASGPR 1
機能Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
組織特異性Expressed exclusively in hepatic parenchymal cells.
配列類似性Contains 1 C-type lectin domain.
翻訳後修飾Phosphorylated on a cytoplasmic Ser residue.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.