Anti-HSV1 ICP0 抗体 [5H7] (ab6513)
![Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)](https://www.abcam.co.jp/ps/products/6/ab6513/Images/ab6513-12352-anti-hsv1-icp0-antibody-5h7-immunofluorescence.jpg "Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)")
Key features and details
- Mouse monoclonal [5H7] to HSV1 ICP0
- Suitable for: WB, ELISA, ICC/IF
- Isotype: IgG1
製品の概要
-
製品名
Anti-HSV1 ICP0 antibody [5H7] -
製品の詳細
Mouse monoclonal [5H7] to HSV1 ICP0 -
由来種
Mouse -
アプリケーション
適用あり: WB, ELISA, ICC/IFmore details -
種交差性
交差種: Other species -
免疫原
Herpes Virus
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.4 -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
5H7 -
ミエローマ
NS1/1-Ag4-1 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab6513の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/8000.
|
|
| ELISA |
1/12800.
|
|
| ICC/IF | (1) |
1/25600.
|
| 特記事項 |
|---|
|
WB
1/8000. |
|
ELISA
1/12800. |
|
ICC/IF
1/25600. |
ターゲット情報
-
関連性
Herpes simplex virus (HSV) encodes four nuclear phosphoproteins that contribute towards the full productive lytic cycle cascade in newly infected permissive cells. The IE175 (or ICP4) and IE63 (or ICP27) proteins have essential regulatory roles during the lytic cycle. A third, IE110 (or ICP0), appears to play only an accessory role in the presence of VP16, but in the absence of VP16 appears to be critical for initiation of reactivated infections. -
細胞内局在
Nuclear -
別名
- Alpha 0 protein antibody
- Herpes siplex virus 1 antibody
- HHV1 ICP0 antibody
see all
画像
-
Immunocytochemistry/ Immunofluorescence - Anti-HSV1 ICP0 antibody [5H7] (ab6513)This image is courtesy of an anonymous Abreviewab6513 (1/25600) staining HSV1 ICP0 in human cells. Cells were PFA-fixed, permeabilized in 0.3% TritonX-100/PBS and blocked in 1% serum /30 minutes /25oC. A fluorescently labeled donkey anti-mouse antibody was used as the secondary.
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (32)
ab6513 は 32 報の論文で使用されています。
- Sun B et al. Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency. Nat Microbiol 6:682-696 (2021). PubMed: 33558653
- Furey C et al. TACC3 Regulates Microtubule Plus-End Dynamics and Cargo Transport in Interphase Cells. Cell Rep 30:269-283.e6 (2020). PubMed: 31914393
- Subramanian G et al. The interferon-inducible protein TDRD7 inhibits AMP-activated protein kinase and thereby restricts autophagy-independent virus replication. J Biol Chem 295:6811-6822 (2020). PubMed: 32273341
- Glanz A et al. High Throughput Screening of FDA-Approved Drug Library Reveals the Compounds that Promote IRF3-Mediated Pro-Apoptotic Pathway Inhibit Virus Replication. Viruses 12:N/A (2020). PubMed: 32295140
- Zou W et al. Degradation of Herpes Simplex Virus-1 Viral miRNA H11 by Vaccinia Virus Protein VP55 Attenuates Viral Replication. Front Microbiol 11:717 (2020). PubMed: 32390978
