Anti-HSV1 ICP0 抗体 [5H7] (ab6513)
Key features and details
- Mouse monoclonal [5H7] to HSV1 ICP0
- Suitable for: WB, ELISA, ICC/IF
- Reacts with: Herpes simplex virus
- Isotype: IgG1
製品の概要
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製品名
Anti-HSV1 ICP0 antibody [5H7] -
製品の詳細
Mouse monoclonal [5H7] to HSV1 ICP0 -
由来種
Mouse -
アプリケーション
適用あり: WB, ELISA, ICC/IFmore details -
種交差性
交差種: Herpes simplex virus -
免疫原
Herpes Virus
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.4 -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
5H7 -
ミエローマ
NS1/1-Ag4-1 -
アイソタイプ
IgG1 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab6513の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/8000.
|
|
ELISA |
1/12800.
|
|
ICC/IF | (1) |
1/25600.
|
特記事項 |
---|
WB
1/8000. |
ELISA
1/12800. |
ICC/IF
1/25600. |
ターゲット情報
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関連性
Herpes simplex virus (HSV) encodes four nuclear phosphoproteins that contribute towards the full productive lytic cycle cascade in newly infected permissive cells. The IE175 (or ICP4) and IE63 (or ICP27) proteins have essential regulatory roles during the lytic cycle. A third, IE110 (or ICP0), appears to play only an accessory role in the presence of VP16, but in the absence of VP16 appears to be critical for initiation of reactivated infections. -
細胞内局在
Nuclear -
参照データベース
- SwissProt: P08393 Herpes simplex virus
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別名
- Alpha 0 protein antibody
- Herpes siplex virus 1 antibody
- HHV1 ICP0 antibody
see all
画像
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ab6513 (1/25600) staining HSV1 ICP0 in human cells. Cells were PFA-fixed, permeabilized in 0.3% TritonX-100/PBS and blocked in 1% serum /30 minutes /25oC. A fluorescently labeled donkey anti-mouse antibody was used as the secondary.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (39)
ab6513 は 39 報の論文で使用されています。
- Malikov V et al. FEZ1 phosphorylation regulates HSPA8 localization and interferon-stimulated gene expression. Cell Rep 38:110396 (2022). PubMed: 35172151
- Jbara-Agbaria D et al. Liposomal siRNA Formulations for the Treatment of Herpes Simplex Virus-1: In Vitro Characterization of Physicochemical Properties and Activity, and In Vivo Biodistribution and Toxicity Studies. Pharmaceutics 14:N/A (2022). PubMed: 35336008
- Wang Z et al. Oleanolic Acid Derivative AXX-18 Exerts Antiviral Activity by Inhibiting the Expression of HSV-1 Viral Genes UL8 and UL52. Viruses 14:N/A (2022). PubMed: 35746758
- Shan T et al. Viral UL8 Is Involved in the Antiviral Activity of Oleanolic Acid Against HSV-1 Infection. Front Microbiol 12:689607 (2021). PubMed: 34354687
- Suryawanshi RK et al. mTORC2 confers neuroprotection and potentiates immunity during virus infection. Nat Commun 12:6020 (2021). PubMed: 34650053