Anti-HSV1 gC Envelope Protein 抗体 [3G9] (ab6509)
Key features and details
- Mouse monoclonal [3G9] to HSV1 gC Envelope Protein
- Suitable for: WB, ELISA, ICC/IF
- Isotype: IgG2a
製品の概要
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製品名
Anti-HSV1 gC Envelope Protein antibody [3G9] -
製品の詳細
Mouse monoclonal [3G9] to HSV1 gC Envelope Protein -
由来種
Mouse -
アプリケーション
適用あり: WB, ELISA, ICC/IFmore details -
種交差性
交差種: Other species -
免疫原
Tissue, cells or virus corresponding to Herpes simplex virus HSV1 gC Envelope Protein. Herpes Virus
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.4 -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
3G9 -
ミエローマ
NS1/1-Ag4-1 -
アイソタイプ
IgG2a -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Conjugation kits
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab6509の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (2) |
1/3200.
|
ELISA |
1/102400.
|
|
ICC/IF |
1/25600.
|
特記事項 |
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WB
1/3200. |
ELISA
1/102400. |
ICC/IF
1/25600. |
ターゲット情報
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関連性
Herpes simplex type 1 (HSV-1) belongs to a family that includes HSV-2, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus amongst others. HSV-1 and HSV-2 are extremely difficult to distinguish from each other. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope, derived from the nuclear membrane of the last host, which is decorated with virus-specific glycoproteins spikes. These viruses are capable of entering a latent phase where the host shows no visible sign of infection and levels of infectious agent become very low. During the latent phase the viral DNA is integrated into the genome of the host cell. -
別名
- Envelope glycoprotein C antibody
- GC antibody
- Glycoprotein C antibody
see all
画像
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Western blot - Anti-HSV1 gC Envelope Protein antibody [3G9] (ab6509)Image from Livingston CM et al., PLoS Pathog. 2009 Oct;5(10):e1000619. Epub 2009 Oct 9.Fig 1.; doi:10.1371/journal.ppat.1000619; October 9, 2009, PLoS Pathog 5(10): e1000619.Western blot analysis of Vero cells mock-infected or infected with KOS at a multiplicity of infection of 10 for 1, 3, 6 and 9 hours.
HSV1 gC Envelope Protein was detected using ab6509, at 1/1000 dilution. An HRP-conjugated sheep-anti-mouse IgG (1/20000) was used as the secondary antibody.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (10)
ab6509 は 10 報の論文で使用されています。
- Murray-Nerger LA et al. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res 49:2044-2064 (2021). PubMed: 33533922
- Saiz-Ros N et al. Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication. Cells 8:N/A (2019). PubMed: 30717447
- Lu H et al. Targeting STT3A-oligosaccharyltransferase with NGI-1 causes herpes simplex virus 1 dysfunction. FASEB J 33:6801-6812 (2019). PubMed: 30811219
- Brun P et al. Herpes Simplex Virus Type 1 Infects Enteric Neurons and Triggers Gut Dysfunction via Macrophage Recruitment. Front Cell Infect Microbiol 8:74 (2018). WB . PubMed: 29600197
- Huang CY et al. Thymidine Kinase-Negative Herpes Simplex Virus 1 Can Efficiently Establish Persistent Infection in Neural Tissues of Nude Mice. J Virol 91:N/A (2017). IHC . PubMed: 27974554
- Santana S et al. Oxidative stress enhances neurodegeneration markers induced by herpes simplex virus type 1 infection in human neuroblastoma cells. PLoS One 8:e75842 (2013). PubMed: 24124518
- Ren Y et al. Glycoprotein M is important for the efficient incorporation of glycoprotein H-L into herpes simplex virus type 1 particles. J Gen Virol 93:319-29 (2012). PubMed: 22012461
- Scheper T et al. The glycoproteins C and G are equivalent target antigens for the determination of herpes simplex virus type 1-specific antibodies. J Virol Methods 166:42-7 (2010). PubMed: 20171247
- Bastian TW & Rice SA Identification of sequences in herpes simplex virus type 1 ICP22 that influence RNA polymerase II modification and viral late gene expression. J Virol 83:128-39 (2009). WB . PubMed: 18971282
- Livingston CM et al. Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection. PLoS Pathog 5:e1000619 (2009). WB . PubMed: 19816571