Anti-HPV18 E6 抗体 [BF7] (ab20192)
Key features and details
- Mouse monoclonal [BF7] to HPV18 E6
- Suitable for: WB, RIA, ELISA
- Isotype: IgG1
製品の概要
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製品名
Anti-HPV18 E6 antibody [BF7] -
製品の詳細
Mouse monoclonal [BF7] to HPV18 E6 -
由来種
Mouse -
アプリケーション
適用あり: WB, RIA, ELISAmore details -
種交差性
交差種: Other species -
免疫原
Fusion protein corresponding to Human papillomavirus HPV18 E6.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: PBS -
Concentration information loading... -
精製度
Protein A/G purified -
ポリ/モノ
モノクローナル -
クローン名
BF7 -
ミエローマ
NS1 -
アイソタイプ
IgG1 -
軽鎖の種類
unknown -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab20192の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use at an assay dependent dilution. Predicted molecular weight: 17 kDa.
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| RIA |
Use at an assay dependent dilution.
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| ELISA |
Use at an assay dependent dilution.
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| 特記事項 |
|---|
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WB
Use at an assay dependent dilution. Predicted molecular weight: 17 kDa. |
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RIA
Use at an assay dependent dilution. |
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ELISA
Use at an assay dependent dilution. |
ターゲット情報
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関連性
The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies. -
参照データベース
- Entrez Gene: 1489088 Other species
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別名
- E6 antibody
- Human papillomavirus type 18 E6 antibody
- Protein E6 antibody
データシートおよび資料
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Datasheet download
参考文献 (3)
ab20192 は 3 報の論文で使用されています。
- Yin S et al. MicroRNA-130a regulated by HPV18 E6 promotes proliferation and invasion of cervical cancer cells by targeting TIMP2. Exp Ther Med 17:2837-2846 (2019). PubMed: 30906471
- Cheng Y et al. Human papillomavirus E6-regulated microRNA-20b promotes invasion in cervical cancer by targeting tissue inhibitor of metalloproteinase 2. Mol Med Rep 16:5464-5470 (2017). PubMed: 28849054
- Banks L et al. Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas. J Gen Virol 68 ( Pt 5):1351-9 (1987). PubMed: 3033140
