Anti-HOPX/HOD 抗体 (ab106251)
Key features and details
- Rabbit polyclonal to HOPX/HOD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-HOPX/HOD antibody
HOPX/HOD 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to HOPX/HOD -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Pig
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免疫原
Recombinant full length protein corresponding to Human HOPX/HOD aa 1-73. (BC014225)
Sequence:MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQKW FKQRLAKWRRSEGLPSECRSVTD
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ポジティブ･コントロール
- Human fetal heart tissue lysate.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 0.184% Tris glycine, 1% BSA -
Concentration information loading... -
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106251の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 8 kDa).
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| 特記事項 |
|---|
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WB
1/500 - 1/1000. Detects a band of approximately 8 kDa (predicted molecular weight: 8 kDa). |
ターゲット情報
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機能
Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor. -
組織特異性
Widely expressed. Expressed in the heart, brain, placenta, lung, skeletal and smooth muscles, uterus, urinary bladder, kidney and spleen. Down-regulated in some types of cancer such as lung cancer, choriocarcinoma, head and neck squamous cell carcinoma and oral squamous cell carcinoma. -
配列類似性
Contains 1 homeobox DNA-binding domain. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 281270 Cow
- Entrez Gene: 84525 Human
- Entrez Gene: 74318 Mouse
- Entrez Gene: 396692 Pig
- Entrez Gene: 171160 Rat
- Omim: 607275 Human
- SwissProt: Q8MJD5 Cow
- SwissProt: Q9BPY8 Human
see all -
製品の状態
There are 2 isoforms produced by alternative splicing. -
別名
- CAMEO antibody
- heart odd homeobox 1 protein antibody
- HOD antibody
see all
画像
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Western blot - Anti-HOPX/HOD antibody (ab106251)Anti-HOPX/HOD antibody (ab106251) at 1/500 dilution + Human fetal heart tissue lysate
Predicted band size: 8 kDa
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab106251 は論文での使用が確認できていません。