Anti-HOMER3 抗体 (ab97438)
Key features and details
- Rabbit polyclonal to HOMER3
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-HOMER3 antibody -
製品の詳細
Rabbit polyclonal to HOMER3 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant protein fragment corresponding to a region within amino acids 55 and 275 of HOMER3 (AAH12113).
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ポジティブ・コントロール
- NT2D1 cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab97438の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
ターゲット情報
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機能
Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses. -
配列類似性
Belongs to the Homer family.
Contains 1 WH1 domain. -
ドメイン
The WH1 domain interacts with the PPXXF motif in GRM1, GRM5, RYR1, RYR2, ITPR1, SHANK 1 and SHANK3. -
細胞内局在
Cytoplasm. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse. Postsynaptic density of neuronal cells. - Information by UniProt
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参照データベース
- Entrez Gene: 9454 Human
- Entrez Gene: 26558 Mouse
- Entrez Gene: 29548 Rat
- Omim: 604800 Human
- SwissProt: Q9NSC5 Human
- SwissProt: Q99JP6 Mouse
- SwissProt: Q9Z2X5 Rat
- Unigene: 720208 Human
see all -
別名
- HOME3_HUMAN antibody
- HOMER 3 antibody
- Homer 3D protein antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab97438 は 1 報の論文で使用されています。
- Pu J et al. Long non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophages. Cell Death Dis 12:1103 (2021). PubMed: 34815380