Anti-HMW Cytokeratin 抗体 [34bE12] (ab776)

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)

Key features and details

  • Mouse monoclonal [34bE12] to HMW Cytokeratin
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG1

製品の概要

  • 製品名

    Anti-HMW Cytokeratin antibody [34bE12]

  • 製品の詳細

    Mouse monoclonal [34bE12] to HMW Cytokeratin

  • 由来種

    Mouse

  • アプリケーション

    適用あり: IHC-Pmore details

  • 種交差性

    交差種: Human

  • 免疫原

    Tissue, cells or virus corresponding to Human HMW Cytokeratin. Solubilized keratin extract from human stratum corneum.

  • 特記事項

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

製品の特性

アプリケーション

The Abpromise guarantee

Abpromise保証は、 次のテスト済みアプリケーションにおけるab776の使用に適用されます

アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。

アプリケーション Abreviews 特記事項
IHC-P
1/25 - 1/50.

Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Enzymatic antigen retrieval of paraffin embedded tissues is recommended prior to immunostaining.
特記事項
IHC-P
1/25 - 1/50.

Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. Enzymatic antigen retrieval of paraffin embedded tissues is recommended prior to immunostaining.

ターゲット情報

  • 関連性

    Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1 (67), CK2 (65.5), CK3 (64), CK4 (59), CK5 (58), CK6 (56), CK7 (54), CK8 (52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16( 48), CK17 (46), CK18 (45), CK19(48) and CK20(46).

  • 細胞内局在

    Cytoplasmic

  • 参照データベース

    see all

  • 別名

    • CK13 antibody
    • CK14 antibody
    • CK15 antibody
    • CK16 antibody
    • Cytokeratin 13 antibody
    • Cytokeratin 14 antibody
    • Cytokeratin 15 antibody
    • Cytokeratin 16 antibody
    • K13 antibody
    • K14 antibody
    • K15 antibody
    • K16 antibody
    • Keratin 13 antibody
    • Keratin 14 antibody
    • Keratin 15 antibody
    • Keratin 15, basic antibody
    • Keratin 15, beta antibody
    • Keratin 16 antibody
    • KRT13 antibody
    • KRT14 antibody
    • KRT15 antibody
    • KRT16 antibody
    • KRT16A antibody
    see all

画像

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)
    Formalin fixed paraffin embedded human prostate tissue, staining HMW Cytokeratin with ab776 in immunohistochemical analysis
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HMW Cytokeratin antibody [34bE12] (ab776)

    ab776 staining human skin tissue sections by IHC-P.

参考文献 (2)

ab776 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

ab776 は 2 報の論文で使用されています。

  • Hermanova I  et al. Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer. J Exp Med 217:N/A (2020). PubMed: 32219437
  • Hagman Z  et al. miR-205 negatively regulates the androgen receptor and is associated with adverse outcome of prostate cancer patients. Br J Cancer 108:1668-76 (2013). IHC ; Human . PubMed: 23571738

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