Anti-Hepatitis C Virus Core Antigen 抗体 [6A1] (ab2582)
Key features and details
- Mouse monoclonal [6A1] to Hepatitis C Virus Core Antigen
- Suitable for: ELISA, IP
- Reacts with: Hepatitis C virus
- Isotype: IgG2a
Related conjugates and formulations
製品の概要
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製品名
Anti-Hepatitis C Virus Core Antigen antibody [6A1]
Hepatitis C Virus Core Antigen 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [6A1] to Hepatitis C Virus Core Antigen -
由来種
Mouse -
特異性
This antibody is specific for Hepatitis C Core Antigen. -
アプリケーション
適用あり: ELISA, IPmore details -
種交差性
交差種: Hepatitis C virus -
免疫原
Recombinant fragment, corresponding to amino acids 2-80 of Hepatitis C Virus Core Antigen
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エピトープ
This antibody recognises amino acid residues 1-80 of Hepatitis C Core Antigen. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.01% Sodium azide -
Concentration information loading...
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ポリ/モノ
モノクローナル -
クローン名
6A1 -
ミエローマ
unknown -
アイソタイプ
IgG2a -
軽鎖の種類
unknown -
研究分野
関連製品
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Alternative Versions
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab2582の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
1/10000.
|
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IP |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
1/10000. |
IP
Use at an assay dependent concentration. |
ターゲット情報
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関連性
The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein; it also participates in some cellular processes, including transcriptional regulation. However the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR. Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Hepatitis C virus (HCV) causes most cases of non-A, non-B hepatitis and results in most HCV infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. T cell responses, including interferon-gamma production are severely suppressed in chronic HCV patients. -
細胞内局在
Endoplasmic reticulum -
参照データベース
- SwissProt: P26664 Hepatitis C virus
- SwissProt: P29846 Hepatitis C virus
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別名
- Core protein p21 antibody
- HCV core antigen antibody
- HCV core protein antibody
- Hepatitis C Virus core protein antibody
データシートおよび資料
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Datasheet download
参考文献 (1)
ab2582 は 1 報の論文で使用されています。
- Draz MS et al. Virus detection using nanoparticles and deep neural network-enabled smartphone system. Sci Adv 6:N/A (2020). PubMed: 33328239