Anti-Hepatitis C Virus 抗体 (ab1035)

Submit a review Q&A (1)References (2)

Key features and details

  • Rabbit polyclonal to Hepatitis C Virus
  • Suitable for: WB
  • Reacts with: Hepatitis C virus
  • Isotype: unknown

製品の概要

  • 製品名

    Anti-Hepatitis C Virus antibody
    Hepatitis C Virus 一次抗体 製品一覧

  • 製品の詳細

    Rabbit polyclonal to Hepatitis C Virus

  • 由来種

    Rabbit

  • 特異性

    This antibody reacts with the 44 kD core protein C3, the envelope protein, and E2 (NS1) of Hepatitis C Virus.

  • アプリケーション

    適用あり: WBmore details

  • 種交差性

    交差種: Hepatitis C virus

  • 免疫原

    Peptide corresponding to amino acids 33-43 of Hepatitis C Virus (HCV) core protein C3.

  • 特記事項

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

製品の特性

  • 製品の状態

    Liquid

  • 保存方法

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

  • バッファー

    pH: 7.4
    Preservative: 0.05% Sodium azide
  • Concentration information loading...

  • 精製度

    Immunogen affinity purified

  • ポリ/モノ

    ポリクローナル

  • アイソタイプ

    unknown

  • 軽鎖の種類

    unknown

  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab1035 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000.

ターゲット情報

  • 関連性

    Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.

  • 細胞内局在

    Virus surface

  • 参照データベース

    • 別名

      • Genome polyprotein antibody
      • HCV antibody
      • Hepatitis C virus polyprotein antibody

    参考文献 (2)

    ab1035 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab1035 は 2 報の論文で使用されています。

    • Munjal C  et al. TGF-ß mediates early angiogenesis and latent fibrosis in an Emilin1-deficient mouse model of aortic valve disease. Dis Model Mech 7:987-96 (2014). IHC . PubMed: 25056700
    • Yuk CS  et al. Development and evaluation of a protein microarray chip for diagnosis of hepatitis C virus. Biotechnol Lett 26:1563-8 (2004). PubMed: 15604797

    レビューと Q&A

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    Question

    I am searching for an antibody to Hepatitis C strain 2a for use with Western blotting. I see that you have several HCV antibodies but could only find information regarding which strain they were raised against for a few. An HCV core protein antibody may be suitable from another strain if it can be used in Western blotting assays but one specifically raised against strain 2a would be best. I would appreciate any further information you might be able to provide and thank you in advance for your time and consideration.

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    Answer

    Thank you for your enquiry. I looked up some Hepatitis C Virus antibodies that may be of interest to you and the information is listed below. It does not appear that we have one that is specific for strain 2a or has even bee tested for reactivity with that strain. Please contact us again if you have any additional questions. Ab20773 - Goat polyclonal to Hepatitis C Virus NS5: Immunogen used was recombinant NS5 a&b genotype 1a (100% of a and 70% of b). This antibody has not been tested for reactivity to genotype 2a. Ab1035 - Rabbit polyclonal to Hepatitis C Virus: Immunogen used was a peptide corresponding to amino acids 33-43 of Hepatitis C Virus (HCV) core protein C3. Ab1033 - Rabbit polyclonal to Hepatitis C Virus: Immunogen used was a peptide corresponding to amino acids 9-21 of Hepatitis C Virus (HCV) core protein C1. For ab1035 and ab1033, strain 2a hasn't been tested, but the understanding is that the sequences derived from core proteins C1 and C3 which were used for immunization are well conserved in the different strains of Hepatitis C virus. Therefore, it is likely that these antibodies will react with Hepatitis C strain 2a. Ab18662 - Mouse monoclonal [24-8 ] to Hepatitis C Virus: Immunogen used was a highly antigenic polypeptide consisting of essential sequences of at least 60 residues in length, which were selected from genes encoding the NS-3 region of Chinese HCV strains. This antibody is not hepatitis C virus[HCV] strain specific, and will recognize the NS3 of HCV strains. If the NS3 variation has been observed in this strain, it may cause the weaker/or non reaction when using this antibody, in the case of the variation is matched the epitope region or interfered the Antibody-Antigen binding-reaction site/sequences. Ab27791 - Goat polyclonal to Hepatitis C Virus: Immunogen used was recombinant chimeric HCV polyprotein (60 kDa). This antibody product will react with various HCV, and the reaction is not HCV strain specific.

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