Anti-Hepatitis B Virus Surface Antigen 抗体 [HB5] (ab8333)

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Key features and details

  • Mouse monoclonal [HB5] to Hepatitis B Virus Surface Antigen
  • Suitable for: ICC, ELISA
  • Reacts with: Hepatitis B virus
  • Isotype: IgG2a

製品の概要

  • 製品名

    Anti-Hepatitis B Virus Surface Antigen antibody [HB5]
    Hepatitis B Virus Surface Antigen 一次抗体 製品一覧

  • 製品の詳細

    Mouse monoclonal [HB5] to Hepatitis B Virus Surface Antigen

  • 由来種

    Mouse

  • 特異性

    Recognizes following Hepatitis B virus subtypes:ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq- Specificity of MAb HB5 was verified by ELISA on panel of International Workshop on HBsAg Subtypes (Paris, April 1975). This antibody does not cross-block with ab8256 and is therefore suitable for use with ab8256 as a matched pair.

  • アプリケーション

    適用あり: ICC, ELISAmore details

  • 種交差性

    交差種: Hepatitis B virus

  • 免疫原

    purified HbsAg from human plasma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab8333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

ターゲット情報

  • 関連性

    Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.

  • 細胞内局在

    Virion membrane

  • 参照データベース

    • 別名

      • Large envelope protein antibody
      • Large surface protein antibody
      • LHB antibody
      • Major surface antigen antibody

    参考文献 (0)

    ab8333 を使用した論文を発表された方は、こちらまでお知らせください。データシートに掲載させていただきます。

    ab8333 は論文での使用が確認できていません。

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    1-2 of 2 Abreviews or Q&A

    Question

    Hi Abcam Tech Support Team,

    May I know which Human HBsAg Monoclonal antibody (i.e. ab110600, ab54247 and ab20724) binds to all four serotypes of Hepatitis B virus?

    I look forward to receiving your reply soon. Many thanks in advance!

    Best regards,

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    Answer

    Thank you for your email.
    We do offer a variety of antibodies that will recognize the four major serotypes: adr, adw, ayr, ayw.
    If it has been tested which serotype is recognizwed by an antibody this information can be found on the datasheet in the "specificity" section.
    Here is a non- exhaustive list of antibodies that bind all four major serotypes. They have even been characterized further and the datasheet will tell you the serotype subtypes (e.g. ayw2, ayw3, ayw4, ayr, adw2, adw4, adrq+, adrq-)also.
    For example:
    ab2039
    https://www.abcam.com/index.html?datasheet=2039 (or use the following: https://www.abcam.com/index.html?datasheet=2039).
    ab8333
    https://www.abcam.com/index.html?datasheet=8333 (or use the following: https://www.abcam.com/index.html?datasheet=8333).
    ab859
    https://www.abcam.com/index.html?datasheet=859 (or use the following: https://www.abcam.com/index.html?datasheet=859).
    ab20724
    https://www.abcam.com/index.html?datasheet=20724 (or use the following: https://www.abcam.com/index.html?datasheet=20724).
    Which antibody is the most suitable for experiments depends on your samples and the planned application.
    We encourage customers to consult the latest literature available through PubMed and other resources in order to find the most up-to-date information about this specific research topic.
    I hope this information is helpful. Please do not hesiate to contact me again with anyfurther questions.

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    Question

    I am interested in developing an Elisa to quantify mouse antibody titres against HBs virus and I am looking for a source of antibody to use as a positive control, I would be interested if you could tell me more information about the mouse monoclonal antibodies against HBs, and if you supply them in France and their price in euro. Thank you.

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    Answer

    All the information that we have is available on the datasheets, this includes the price in euros. You can order directly through the Abcam website or if you would prefer you can order from a distributor. There is an ordering section on the Abcam website which has full details, simply click on the flag of your country.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com