Key features and details
- Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
- Suitable for: IHC-P, IHC-Fr
- Reacts with: Hepatitis B virus
- Isotype: IgG1
製品名Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted
Hepatitis B Virus Surface Antigen 一次抗体 製品一覧
製品の詳細Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
特異性This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
アプリケーション適用あり: IHC-P, IHC-Frmore details
種交差性交差種: Hepatitis B virus
BALB/c mice were immunized with purified HBsAG subtype AYW3.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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保存方法Shipped at 4°C. Store at +4°C. Do Not Freeze.
バッファーPreservative: 0.05% Sodium azide
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Our Abpromise guarantee covers the use of ab859 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
関連性Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody