Anti-Hepatitis B Virus Surface Antigen 抗体 [3E7], prediluted (ab859)
製品の概要
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製品名Anti-Hepatitis B Virus Surface Antigen antibody [3E7], prediluted
Hepatitis B Virus Surface Antigen 一次抗体 製品一覧 -
製品の詳細Mouse monoclonal [3E7] to Hepatitis B Virus Surface Antigen, prediluted
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由来種Mouse
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特異性This antibody stains the cytoplasm of antigen-positive liver cells in patients with Type B viral hepatitis. This antibody reacts with the ‘a’ determinant present on the HBsAg subtypes ayw1, ayw2, ayw3, ayw4, ayr, adw2, adw4 and adr. It does not react with normal tissues.
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アプリケーション適用あり: IHC-P, IHC-Frmore details
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種交差性交差種: Hepatitis B virus
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免疫原
BALB/c mice were immunized with purified HBsAG subtype AYW3.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C. Do Not Freeze.
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バッファーPreservative: 0.05% Sodium azide
Inert stabilizer -
Concentration information loading... -
ポリ/モノモノクローナル
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クローン名3E7
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ミエローマunknown
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アイソタイプIgG1
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab859 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P | ||
| IHC-Fr |
追加情報
This antibody has been pretitered and quality controlled to work on formalin-fixed paraffin-embedded as well as acetone fixed cryostat tissue sections.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
No further titration is required.
We suggest an incubation period of 60 minutes at room temperature.
However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.
ターゲット情報
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関連性Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.
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細胞内局在Virion membrane
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参照データベース
- Entrez Gene: 2703546 Hepatitis B virus
- SwissProt: P03142 Hepatitis B virus
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別名
- Large envelope protein antibody
- Large surface protein antibody
- LHB antibody
- Major surface antigen antibody
参考文献
ab859 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"