Anti-GABRB1 抗体 (ab16703)
Key features and details
- Rabbit polyclonal to GABRB1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-GABRB1 antibody
GABRB1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to GABRB1 -
由来種
Rabbit -
特異性
Reacts with the 51-54 kDa beta 1 subunit of rat brain GABA A. There is no homology or known reactivity with other GABA subunits. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Rat GABRB1.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.50
Constituents: 0.238% HEPES, 50% Glycerol, 0.87% Sodium chloride, 0.01% BSA -
Concentration information loading...
-
精製度
Protein A purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab16703の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/1000. Predicted molecular weight: 53 kDa.
|
特記事項 |
---|
WB
1/1000. Predicted molecular weight: 53 kDa. |
ターゲット情報
-
機能
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. -
配列類似性
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRB1 sub-subfamily. -
細胞内局在
Cell junction > synapse > postsynaptic cell membrane. Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 2560 Human
- Omim: 137190 Human
- SwissProt: P18505 Human
- Unigene: 27283 Human
-
別名
- AW061132 antibody
- B230208N19Rik antibody
- GABA(A) receptor beta 1 antibody
see all
画像
-
All lanes : Anti-GABRB1 antibody (ab16703) at 1/1000 dilution
Lane 1 : Cerebellum lysate
Lane 2 : Cortex lysate
Predicted band size: 53 kDa
Observed band size: 51 kDa why is the actual band size different from the predicted?
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (4)
ab16703 は 4 報の論文で使用されています。
- Sabanov V et al. Impaired GABAergic inhibition in the hippocampus of Fmr1 knockout mice. Neuropharmacology 116:71-81 (2017). PubMed: 28012946
- Quintana A et al. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci 15:1547-55 (2012). Mouse . PubMed: 23064379
- Adusei DC et al. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology 59:167-71 (2010). WB ; Mouse . PubMed: 20470805
- Jin N et al. Ionotropic GABA receptor expression in the lung during development. Gene Expr Patterns 8:397-403 (2008). WB, IHC-P ; Rat . PubMed: 18539546