FITC Anti-HLA DR + HLA DP 抗体 [HL-38], prediluted (ab18232)
Key features and details
- FITC Mouse monoclonal [HL-38] to HLA DR + HLA DP, prediluted
- Reacts with: Human, Pig
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2a
製品の概要
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製品名
FITC Anti-HLA DR + HLA DP antibody [HL-38], prediluted
HLA DR + HLA DP 一次抗体 製品一覧 -
製品の詳細
FITC Mouse monoclonal [HL-38] to HLA DR + HLA DP, prediluted -
由来種
Mouse -
標識
FITC. Ex: 493nm, Em: 528nm -
種交差性
交差種: Human, Pig -
免疫原
Tissue, cells or virus corresponding to Human HLA DR + HLA DP. Burkitts lymphoma cell line Raji
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エピトープ
This antibody recognizes a common epitope on the beta chain of human HLA DR and HLA DP. -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: PBS, BSA -
Concentration information loading... -
ポリ/モノ
モノクローナル -
クローン名
HL-38 -
アイソタイプ
IgG2a -
研究分野
関連製品
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Isotype control
アプリケーション
追加情報
Flow Cyt: Use 20 µl of reagent per 100 µl of whole blood.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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関連性
Human MHC class II antigens are transmembrane glycoproteins composed of an alpha (36 kDa) and a beta chain (27kDa) and are expressed primarily on antigen presenting cells. Human MHC class II genes are located in the HLA-D region that encodes at least 6 alpha and 10 beta chain genes. Three loci, DR, DQ and DP, encode the major products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells and therefore have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. -
細胞内局在
Cell Membrane; Single pass type I membrane protein -
参照データベース
- Entrez Gene: 3115 Human
- Entrez Gene: 3122 Human
- Entrez Gene: 3123 Human
- Entrez Gene: 3125 Human
- Entrez Gene: 3126 Human
- Entrez Gene: 3127 Human
- Entrez Gene: 972 Human
- Omim: 142858 Human
see all -
別名
- HLA DP antibody
- HLA DR antibody
- MHC Class II antibody
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab18232 は 1 報の論文で使用されています。
- Do HV et al. Characterization of Insulin-Secreting Porcine Bone Marrow Stromal Cells Ex Vivo and Autologous Cell Therapy In Vivo. Cell Transplant 24:1205-20 (2015). PubMed: 24667101