FITC Anti-F4/80 抗体 [CI:A3-1] (ab105155)
Key features and details
- FITC Rat monoclonal [CI:A3-1] to F4/80
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: FITC. Ex: 493nm, Em: 528nm
- Isotype: IgG2b
Related conjugates and formulations
製品の概要
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製品名
FITC Anti-F4/80 antibody [CI:A3-1]
F4/80 一次抗体 製品一覧 -
製品の詳細
FITC Rat monoclonal [CI:A3-1] to F4/80 -
由来種
Rat -
標識
FITC. Ex: 493nm, Em: 528nm -
特異性
ab105155 recognises the murine F4/80 antigen. -
アプリケーション
適用あり: Flow Cytmore details -
種交差性
交差種: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse F4/80. Thioglycollate stimulated peritoneal macrophages from C57/BL mice.
Database link: Q61549 -
ポジティブ・コントロール
- Mouse peritoneal macrophages
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特記事項
Clone CI:A3-1 has been reported to modulate cytokine levels released in response to Listeria monocytogenes.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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精製度
Protein G purified -
一次抗体 備考
Clone CI:A3-1 has been reported to modulate cytokine levels released in response to Listeria monocytogenes. -
ポリ/モノ
モノクローナル -
クローン名
CI:A3-1 -
ミエローマ
NS1 -
アイソタイプ
IgG2b -
軽鎖の種類
kappa -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab105155の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
Flow Cyt |
Use 10µl for 106 cells.
in 100ul. ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
特記事項 |
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Flow Cyt
Use 10µl for 106 cells. in 100ul. ab136125 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
ターゲット情報
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機能
Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. -
組織特異性
Expression is restricted to eosinophils. -
配列類似性
Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
Contains 6 EGF-like domains.
Contains 1 GPS domain. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 13733 Mouse
- SwissProt: Q61549 Mouse
- Unigene: 2254 Mouse
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別名
- ADGRE1 antibody
- Adhesion G protein coupled receptor E1 antibody
- Adhesion G protein-coupled receptor E1 antibody
see all
画像
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Flow cytometry staining of mouse peritoneal macrophages with ab105155.
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FSC/SSC gated mouse peritoneal macrophages dual stained with ab105155 at 1/5 dilution and anti-CD11b at 1/5 dilution by Flow cytometry. Isotype control pair in red. Fc receptors were blocked.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (14)
ab105155 は 14 報の論文で使用されています。
- Stahl EC et al. Inflammation and Ectopic Fat Deposition in the Aging Murine Liver Is Influenced by CCR2. Am J Pathol 190:372-387 (2020). PubMed: 31843499
- Mohamad NE et al. Apoptosis and metastasis inhibitory potential of pineapple vinegar against mouse mammary gland cells in vitro and in vivo. Nutr Metab (Lond) 16:49 (2019). PubMed: 31372176
- Kim H et al. Exosome-Guided Phenotypic Switch of M1 to M2 Macrophages for Cutaneous Wound Healing. Adv Sci (Weinh) 6:1900513 (2019). PubMed: 31637157
- Rodríguez MM et al. 4Mu Decreases CD47 Expression on Hepatic Cancer Stem Cells and Primes a Potent Antitumor T Cell Response Induced by Interleukin-12. Mol Ther 26:2738-2750 (2018). PubMed: 30301668
- Rayagiri SS et al. Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal. Nat Commun 9:1075 (2018). PubMed: 29540680