FFN206, fluorescent VMAT2 substrate (ab144554)
Key features and details
- Novel and highly fluorescent VMAT2 substrate
- CAS Number: 1447064-50-7
- Purity: > 95%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
FFN206, fluorescent VMAT2 substrate -
製品の詳細
Novel and highly fluorescent VMAT2 substrate -
生理活性の詳細
Novel and highly fluorescent VMAT2 substrate. Enables quantitative and high throughput examination of VMAT2. Detects VMAT2 activity in intact cells (Km = 1.16 µM). Allows optical examination of VMAT2 function in cell culture.
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精製度
> 95% -
CAS 番号
1447064-50-7 -
構造式
製品の特性
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体系名
4-(2-Aminoethyl)-7-(methylamino)-2H-chromen-2-one trifluoroacetate -
分子量
389.29 -
分子式
C12H14N2O2.1.5CF3CO2H -
PubChem 登録番号
137699583 -
保存方法
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 100 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
FC(F)(F)C(=O)O.FC(F)(F)C(=O)O.CNc1ccc2c(c1)OC(=O)C=C2CCN.CNc1ccc2c(c1)OC(=O)C=C2CCN.CNc1ccc2c(c1)OC(=O)C=C2CCN -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
参考文献 (3)
ab144554 は 3 報の論文で使用されています。
- Zhou H et al. Glia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice. Cell 181:590-603.e16 (2020). PubMed: 32272060
- Iannielli A et al. Reconstitution of the Human Nigro-striatal Pathway on-a-Chip Reveals OPA1-Dependent Mitochondrial Defects and Loss of Dopaminergic Synapses. Cell Rep 29:4646-4656.e4 (2019). PubMed: 31875567
- Liu S et al. Zoledronate modulates intracellular vesicle trafficking in mast cells via disturbing the interaction of myosinVa/Rab3a and sytaxin4/VAMP7. Biochem Pharmacol 151:18-25 (2018). PubMed: 29454616