Anti-FAM120A/OSSA 抗体 (ab106454)
Key features and details
- Rabbit polyclonal to FAM120A/OSSA
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-FAM120A/OSSA antibody
FAM120A/OSSA 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to FAM120A/OSSA -
由来種
Rabbit -
特異性
ab106454 will not cross-react with FAM120B / PGCC1. -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human FAM120A/OSSA (internal sequence).
Database link: NP_055427 -
ポジティブ･コントロール
- SK-N-SH cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106454の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa.
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| 特記事項 |
|---|
|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 122 kDa. |
ターゲット情報
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機能
May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in environments with various oxidative stresses. -
組織特異性
Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared with normal gastric mucosa (at protein level). -
配列類似性
Belongs to the constitutive coactivator of PPAR-gamma family. -
翻訳後修飾
Arg-982 is dimethylated, probably to asymmetric dimethylarginine.
Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure. -
細胞内局在
Cytoplasm. Cell membrane. Translocates to plasma membrane upon ultraviolet exposure. - Information by UniProt
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参照データベース
- Entrez Gene: 23196 Human
- GenBank: NP_055427.2 Human
- Omim: 612265 Human
- SwissProt: Q9NZB2 Human
- Unigene: 372003 Human
- Unigene: 707324 Human
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別名
- C9orf10 antibody
- Chromosome 9 open reading frame 10 antibody
- Constitutive coactivator of PPAR gamma like protein 1 antibody
see all
画像
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Western blot - Anti-FAM120A/OSSA antibody (ab106454)Lane 1 : Anti-FAM120A/OSSA antibody (ab106454) at 0.5 µg/ml
Lane 2 : Anti-FAM120A/OSSA antibody (ab106454) at 1 µg/ml
All lanes : SK-N-SH cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 122 kDa
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (1)
ab106454 は 1 報の論文で使用されています。
- Zheng G et al. TMEM43-S358L mutation enhances NF-?B-TGFß signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Protein Cell N/A:N/A (2018). PubMed: 29980933
