Recombination 2018 952x200

Mechanisms of Recombination conference

Present, discuss, and collaborate! 

Wellcome Genome Campus Conference Centre, Hinxton, Cambridge, UK
April 29 - May 3, 2020


Genetic recombination provides an important mechanism for the repair of chromosome breaks caused by DNA damage or replication fork demise. Defects in the recombination process have been linked to cancer predisposition, in particular breast cancers caused by mutations in BRCA1, BRCA2 and PALB2, and also acute leukemias associated with the rare genetic disease Fanconi anemia. Understanding precisely how recombination occurs is of interest to workers in the fields of meiosis, DNA repair, replication, chromosome architecture and interactions, and chromatin biology.



  • Recombination mechanisms
  • Links between replication and recombination 
  • Maintenance of genome stability 
  • Chromosome interactions and meiosis


Keynote speaker

Confirmed speakers

  • Kara Bernstein (University of Pittsburgh Cancer Institute, US)
    RAD51 paralog function in DNA damage tolerance
  • Valerie Borde (Institut Curie, France)
  • Simon Boulton (The Francis Crick Institute, UK)
    Single molecule analysis of homologous recombination
  • Petr Cejka (Institute for Research in Biomedicine, Switzerland)
    The action of nucleases in homologous recombination
  • Titia de Lange (The Rockefeller University, US)
    The role of CST/Polalpha/Primase in DSB repair
  • Bernard de Massy (Institute of Human Genetics, France)
    Insight into the architecture of the meiotic DNA double-strand break complex
  • Eric Greene (Columbia University, US)
    Single molecule studies of homologous recombination
    Single molecule studies of homologous recombination
    Single molecule studies of homologous recombination

  • James Haber (Brandeis University, US)
    Recombination involving homology, homeology and microhomology
  • Wolf-Dietrich Heyer (University of California, Davis, US)
    D-loop processing during homologous recombination
  • Ian Hickson (University of Copenhagen, Denmark)
    Recombination-based DNA synthesis at common fragile sites
  • Neil Hunter (University of California, Davis, US)
    Essential roles of the small ubiquitin-like modifier in meiotic recombination
  • Grzegorz Ira (Baylor College of Medicine, US)
    Large DNA insertions at DNA double strand breaks
  • Maria Jasin (Memorial Sloan Kettering Cancer Institute, US)
    Protecting the genome by homologous recombination
  • Roland Kanaar (Erasmus University, Netherlands)
    Function of BRCA2 in homologous recombination
  • Scott Keeney (Memorial Sloan Kettering Cancer Institute, US)
    Mechanism and regulation of meiotic recombination initiation
  • Sarah Lambert (Institut Curie, France)
    Replication fork restart in space and time
  • Michael Lichten (National Institutes of Health, US)
    Exploring the inner workings of meiotic recombination
  • Massimo Lopes (Institute of Molecular Cancer Research, Switzerland)
    Replication fork remodelling in cancer and stem cells
  • Kenneth Marians (Memorial Sloan Kettering Cancer Institute, US)
  • Joao Matos (ETH Zurich, Switzerland)
    Regulatory control of BLM/Sgs1 helicase during mitotic proliferation and meiosis
  • John Petrini (Memorial Sloan Kettering Cancer Institute, US)
  • Rodney Rothstein (Columbia University, US)
    Poetry in motion: increased chromosomal mobility after DNA damage
  • Ralph Scully (Harvard Medical School, US)
    Repair and restart of stalled forks in mammalian cells
  • Akira Shinohara (Osaka University, Japan)
    Control of the assembly of RAD51/DMC1 by mediators and anti-recombinases
  • Lorraine Symington (Columbia University, US)
    Mechanism and regulation of DNA end resection
  • Anne Villeneuve (Stanford University, US)
  • Stephen West (The Francis Crick Institute, UK)
    Sensitisation of BRCA cancer cells to PARP inhibition by targeting nucleotide metabolism
  • Xiaolan Zhao (Memorial Sloan Kettering Cancer Institute, US)
    SUMO-based regulation of recombinational repair

Scientific organizer

Call for abstracts

Short talk and poster presentation places are available. Abstracts can be submitted during online registration.


Early bird

before December 6, 2019

before January 31, 2020


before March 20, 2020

Delegate - single£995£1195£1395
Student - single£895£1095


Delegate - twin*£895£1095£1295
Student - twin*£795£995£1195

Registration fee includes:

  • Attendance to scientific sessions and conference materials
  • Dedicated poster sessions
  • Breakfast, refreshments, lunches and dinners during the conference
  • Networking and drinks reception
  • On-site, en-suite accommodation on nights of April 29, April 30, May 1, May 2, 2020**

    * Twin occupancy are only available to people who nominate a roommate (in the special requirements section of the online registration form). Abcam will not pair people together to share rooms.

    ** Accommodation includes breakfast and taxes but do not include extras, eg. mini bar, laundry, etc.

Only a limited number of places are available for this conference and these will be allocated on a first come, first served basis. The previous meeting was sold out! Please book early to avoid disappointment!

Conference venue: The Wellcome Genome Campus Conference Centre

Confirmation note: All registered attendees will receive a email confirmation from within 48 hours of registering. If you do not receive this confirmation email, please contact the Abcam Events Team to confirm your registration.


Start: Wednesday, April 29, 2020 - 3:00pm             
Finish: Sunday, May 3, 2020 - 10:00am

* Note, these times are provsional and subject to change.


​​The conference will take place at the Wellcome Genome Campus Conference Centre in Hinxton, near Cambridge. 

The Wellcome Genome Campus Conference Centre is a beautiful complex within the Hinxton Hall Estate and its 125-acre parkland bordering the River Cam.  It is located alongside research institutions that are both at the forefront of the biomedical revolution and home to life-changing scientific history, creating a unique combination of atmosphere, history and cutting-edge science.


On-site, en-suite accommodation is included in the registration fee.

* Important note *
Abcam does not have an affiliated hotel agency for this event.
Please be careful of direct approaches from companies offering hotel reservations for this event. Reservations made by unaffiliated organizations may appear to be for lower rates, however they may be illegitimate, have unreasonable cancelation or change penalties, or be completely non-refundable. Please be aware of, and report any unauthorized solicitation to Abcam.

Terms and conditions

  • Delegates are advised to ensure they have adequate travel insurance to cover their attendance at the conference in case of incident, or cancelation due to circumstances beyond Abcam's control.
  • All fees payable to Abcam are non-refundable.
  • Substitute delegates can be made at any time by contacting the Abcam Events Team.

Frequently asked questions

  • How can I submit an abstract?
    Abstracts can be submitted through the online registration process. 
  • What happens if I've registered but cannot attend?
    Substitute delegates can be nominated at any time by contacting the Abcam Events Team.
  • Do I need insurance?
    As before any travel, delegates are strongly advised to ensure they have adequate medical and travel insurance.
  • What do I need to get into the country? 
    Please ensure you have an up-to-date passport before booking travel and are aware of any visa requirements which may be in operation for nationals of your country.
  • Are there exhibition and/or sponsorship opportunities?​
    Sponsorship and exhibition opportunities are available for this conference. If you are interested in sponsoring or exhibiting, please e-mail the Abcam Events Team for more information.
  • Have a question?​
    Please contact the Abcam Events Team.