製品の概要

  • 製品名

    Evans blue, L-glutamate uptake inhibitor
  • 製品の詳細

    Potent inhibitor of L-glutamate uptake
  • 生理活性の詳細

    Potent inhibitor of L-glutamate uptake via the membrane bound excitatory amino acid transporter (EAAT). Able to antagonize AMPA and kainate receptor mediated currents (IC50 values are 220 and 150 nM, respectively). Binds with high affinity to serum albumin.

    Also available in simple stock solutions (ab146727) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度

    > 95%
  • CAS 番号

    314-13-6
  • 構造式

    Chemical Structure

製品の特性

参考文献

This product has been referenced in:

  • Emanueli C  et al. Acute ACE inhibition causes plasma extravasation in mice that is mediated by bradykinin and substance P. Hypertension 31:1299-304 (1998). Read more (PubMed: 9622145) »
  • Price CJ & Raymond LA Evans blue antagonizes both alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate and kainate receptors and modulates receptor desensitization. Mol Pharmacol 50:1665-71 (1996). Read more (PubMed: 8967991) »
See 1 Publication for this product

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