Esmolol, beta1 receptor antagonist (ab146018)
Key features and details
- Short-acting cardioselective β1 receptor antagonist. Antiarrhythmic agent.
- CAS Number: 81147-92-4
- Purity: > 98%
- Soluble in water to 25 mM
- Form / State: Solid
- Source: Synthetic
製品の概要
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製品名
Esmolol, beta1 receptor antagonist -
製品の詳細
Short-acting cardioselective β1 receptor antagonist. Antiarrhythmic agent. -
別名
- Beta 1 receptor antagonist
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生理活性の詳細
Short-acting cardioselective β1 receptor antagonist. Antiarrhythmic agent. Reversibly inhibits Na+ inward currents (IC50 = 74 μM). Shows antihypertensive effects in vivo. Orally active.
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精製度
> 98% -
CAS 番号
81147-92-4 -
構造式
製品の特性
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体系名
Methyl 3-[4-(2-hydroxy-3-propan-2-ylamino-propoxy)phenyl]propanoate -
分子量
295.37 -
分子式
C16H25NO4 -
PubChem 登録番号
59768 -
保存方法
Store at +4°C. The product can be stored for up to 12 months. -
溶解性
Soluble in water to 25 mM -
使用に関する注意
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES 線形表記
CC(C)NCC(COC1=CC=C(C=C1)CCC(=O)OC)O -
由来
Synthetic
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研究分野
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab146018 は 1 報の論文で使用されています。
- Pollak AJ et al. A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. Elife 7:N/A (2018). PubMed: 30520731