製品の概要

  • 製品名

    Equol, Metabolite of phytoestrogen daidzein
  • 製品の詳細

    Metabolite of phytoestrogen daidzein
  • 生理活性の詳細

    Isoflavan metabolite produced by the reduction of daidzein (ab120391) by gut micro-organisms. Shown to have estrogenic activity in human breast cancer cells.
  • 精製度

    > 98%
  • CAS 番号

    94105-90-5
  • 構造式

    Chemical Structure

製品の特性

関連製品

参考文献

This product has been referenced in:

  • Brown NM  et al. The chemopreventive action of equol enantiomers in a chemically induced animal model of breast cancer. Carcinogenesis 31:886-93 (2010). Read more (PubMed: 20110282) »
  • Setchell KD & Clerici C Equol: history, chemistry, and formation. J Nutr 140:1355S-62S (2010). Read more (PubMed: 20519412) »
  • Matsumura A  et al. Comparative study of oestrogenic properties of eight phytoestrogens in MCF7 human breast cancer cells. J Steroid Biochem Mol Biol 94:431-43 (2005). Read more (PubMed: 15876408) »

レビューと Q&A

1-3 of 3 Abreviews or Q&A

Answer


ab120390 is a racemic compound and therefore contains both enantiomers (S)-Equol and (R)-Equol. As for the applications it should be used in, I would suggest searching the literature for how other researchers have used this product.

I would also suggest the following publication which I think may be of interest to you:

http://jn.nutrition.org/content/140/7/1363S.full
Kenneth D. R. Setchell and Carlo Clerici, Equol: Pharmacokinetics and Biological Actions

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Question
Answer

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I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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Answer

Thank you for contacting Abcam.

We have been supplying Equol since August 2010. It is the racemic compound and therefore not exactly the same as (S)-Equol which is a single enantiomer. Our material contains an equal amount of (R)-Equol.

Please let me know if there is anything else I can help you with.

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