Anti-EPHA10 抗体 (ab106437)
Key features and details
- Rabbit polyclonal to EPHA10
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-EPHA10 antibody -
製品の詳細
Rabbit polyclonal to EPHA10 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to 14 aa from near the N-terminus of Human EPHA10 (NP_001092909).
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ポジティブ・コントロール
- 293 cell lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106437の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 110 kDa.
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特記事項 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 110 kDa. |
ターゲット情報
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機能
Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5. -
組織特異性
Mainly expressed in testis. -
配列類似性
Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Contains 2 fibronectin type-III domains.
Contains 1 protein kinase domain.
Contains 1 SAM (sterile alpha motif) domain. -
ドメイン
The protein kinase domain is predicted to be catalytically inactive. -
細胞内局在
Secreted and Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 284656 Human
- Omim: 611123 Human
- SwissProt: Q5JZY3 Human
- Unigene: 129435 Human
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製品の状態
Ephrin receptors, the largest subfamily of receptor tyrosine kinases, and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility in neuronal and epithelial cells. There are 3 isoforms produced by alternative splicing. Isoform 2 known as Epha10s, Isoform 3 known as Epha10*. -
別名
- EPH receptor A10 antibody
- EPHA 10 antibody
- Epha10 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab106437 は 2 報の論文で使用されています。
- Peng J & Zhang D Coexpression of EphA10 and Gli3 promotes breast cancer cell proliferation, invasion and migration. J Investig Med 69:1215-1221 (2021). PubMed: 33990369
- Zhang J et al. Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo. Drug Deliv 25:723-737 (2018). PubMed: 29513049