Anti-ENC1 抗体 (ab106683)
Key features and details
- Chicken polyclonal to ENC1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgY
製品の概要
-
製品名
Anti-ENC1 antibody
ENC1 一次抗体 製品一覧 -
製品の詳細
Chicken polyclonal to ENC1 -
由来種
Chicken -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Mouse -
免疫原
Synthetic peptide corresponding to Human ENC1 (internal sequence). The immunogen is located within amino acids 230 - 280 (13 amino acid synthetic peptide) of ENC-1.
Database link: O14682 -
ポジティブ･コントロール
- WB: Mouse kidney muscle tissue lysate.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
ab106683 is purified by affinity chromatography via a peptide column. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgY -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab106683の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 66 kDa.
|
| 特記事項 |
|---|
|
WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 66 kDa. |
ターゲット情報
-
機能
Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. May be down-regulated in neuroblastoma tumors. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. -
組織特異性
Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in adult brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in adult pancreas. -
パスウェイ
Protein modification; protein ubiquitination. -
配列類似性
Contains 1 BTB (POZ) domain.
Contains 6 Kelch repeats. -
発生段階
Dramatically up-regulated upon neuronal differentiation. -
翻訳後修飾
Ubiquitinated and probably targeted for proteasome-independent degradation. -
細胞内局在
Nucleus matrix. Cytoplasm > cytoskeleton. - Information by UniProt
-
参照データベース
- Entrez Gene: 13803 Mouse
- SwissProt: O35709 Mouse
- Unigene: 241073 Mouse
-
別名
- CCL 28 antibody
- CCL28 antibody
- Ectoderm neural cortex protein 1 antibody
see all
画像
-
Western blot - Anti-ENC1 antibody (ab106683)All lanes : Anti-ENC1 antibody (ab106683) at 1 µg/ml
Lane 1 : Mouse Kidney muscle tissue lysate
Lane 2 : Mouse Kidney muscle tissue lysate
with blocking peptide
Lysates/proteins at 15 µg per lane.
Predicted band size: 66 kDa
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (1)
ab106683 は 1 報の論文で使用されています。
- Li X et al. Long Non-coding RNA MIAT Knockdown Prevents the Formation of Intracranial Aneurysm by Downregulating ENC1 via MYC. Front Physiol 11:572605 (2020). PubMed: 33551826
