Anti-EHF 抗体 (ab272671)
Key features and details
- Rabbit polyclonal to EHF
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-EHF antibody
EHF 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to EHF -
由来種
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species IHC-P Human
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免疫原
Recombinant fragment corresponding to Human EHF aa 1-100.
Database link: Q9NZC4 -
ポジティブ･コントロール
- IHC-P: Human salivary and breast tissue.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS -
Concentration information loading... -
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
アプリケーション
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab272671 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| アプリケーション | Species |
|---|---|
| IHC-P |
Human
|
| All applications |
Mouse
Cow
Chimpanzee
|
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
| 特記事項 |
|---|
|
IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene. -
組織特異性
Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, prostate, and lung. Weakly expressed in kidney and colon. Not detected in heart, brain, placenta, liver, skeletal muscle, spleen, thymus, testis, ovary, small intestine or peripheral blood leukocytes. -
配列類似性
Belongs to the ETS family.
Contains 1 ETS DNA-binding domain.
Contains 1 PNT (pointed) domain. -
ドメイン
The PNT domain acts as a transcriptional activator. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 739336 Chimpanzee
- Entrez Gene: 505422 Cow
- Entrez Gene: 26298 Human
- Entrez Gene: 13661 Mouse
- Omim: 605439 Human
- SwissProt: A2T737 Chimpanzee
- SwissProt: Q32LN0 Cow
- SwissProt: Q9NZC4 Human
see all -
別名
- EHF antibody
- EHF_HUMAN antibody
- Epithelium-specific Ets transcription factor 3 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EHF antibody (ab272671)
Paraffin-embedded formalin-fixed human salivary tissue stained for EHF using ab272671 at 1/200 dilution in immunohistochemical analysis.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EHF antibody (ab272671)Paraffin-embedded formalin-fixed human breast tissue stained for EHF using ab272671 at 1/200 dilution in immunohistochemical analysis.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EHF antibody (ab272671)Paraffin-embedded formalin-fixed human liver tissue stained for EHF using ab272671 at 1/200 dilution in immunohistochemical analysis. Shows no expression as expected.
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
参考文献 (0)
ab272671 は論文での使用が確認できていません。
