Anti-EFHD2/SWS1 抗体 (ab24368)
Key features and details
- Goat polyclonal to EFHD2/SWS1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-EFHD2/SWS1 antibody
EFHD2/SWS1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to EFHD2/SWS1 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Dog
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免疫原
Synthetic peptide corresponding to Human EFHD2/SWS1 aa 230-240 (C terminal).
Sequence:(C)AAFKELQSTFK
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ポジティブ･コントロール
- WB: Human thymus, lymph node and tonsil lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading... -
精製度
Immunogen affinity purified -
特記事項（精製）
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab24368の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 28-30 kDa.
1 hour primary incubation is recommended for this product. |
| 特記事項 |
|---|
|
WB
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 28-30 kDa. 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance. -
組織特異性
Found in lymphocytes; preferentially expressed in CD8+ cells. -
配列類似性
Contains 2 EF-hand domains. -
細胞内局在
Membrane raft. In immature B-cell line WEHI231. - Information by UniProt
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参照データベース
- Entrez Gene: 79180 Human
- Entrez Gene: 27984 Mouse
- Entrez Gene: 298609 Rat
- SwissProt: Q96C19 Human
- SwissProt: Q9D8Y0 Mouse
- SwissProt: Q4FZY0 Rat
- Unigene: 465374 Human
- Unigene: 395598 Mouse
see all -
別名
- EF hand domain containing protein 2 antibody
- EF hand domain family, member D2 antibody
- EF-hand domain-containing protein D2 antibody
see all
画像
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Western blot - Anti-EFHD2/SWS1 antibody (ab24368)All lanes : Anti-EFHD2/SWS1 antibody (ab24368) at 0.5 µg/ml
Lane 1 : Human thymus lysate
Lane 2 : Human lymph node lysate
Lane 3 : Human tonsil lysate
Lysates/proteins at 35 µg per lane.Western blot analysis labeling EFHD2/SWS1 with ab24368 at 0.5 ug/ml.
プロトコール
データシートおよび資料
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Datasheet download
参考文献 (3)
ab24368 は 3 報の論文で使用されています。
- Wang Y et al. Schisandrin C attenuates renal damage in diabetic nephropathy by regulating macrophage polarization. Am J Transl Res 13:210-222 (2021). PubMed: 33527019
- Zhang S et al. Swiprosin-1 deficiency impairs macrophage immune response of septic mice. JCI Insight 3:N/A (2018). PubMed: 29415882
- Borger E et al. The calcium-binding protein EFhd2 modulates synapse formation in vitro and is linked to human dementia. J Neuropathol Exp Neurol 73:1166-82 (2014). WB . PubMed: 25383639
